Vibrocil nasal drops 15 ml — Made in Switzerland — Free Delivery

Pharmacological properties

Vibrocil is a combined preparation containing phenylephrine and dimethindene.

The preparation reduces nasal discharge and helps to cleanse the nasal passages without disturbing the physiological functions of the ciliated epithelium and nasal mucosa.

Phenylephrine belongs to the sympathomimetic amines. It is used as a nasal decongestant with a moderate vasoconstrictor effect, selectively stimulates the α1-adrenergic receptors of the cavernous venous tissue of the nasal mucosa. Thus, it quickly and permanently eliminates the swelling of the nasal mucosa and its paranasal sinuses.

Dimetindene, an antagonist of histamine H1 receptors, has antiallergic effect, is effective when used in low doses, and is well tolerated.

Vibrocil is applied topically, so its activity does not correlate with the concentration of active substances in the blood plasma.

In case of accidental oral absorption, the bioavailability of phenylephrine decreased and amounted to about 38%, T1 / 2 - about 2.5 hours.

The systemic bioavailability of dimethindene after oral administration in solution is about 70%, T1 / 2 - about 6 hours.

Indications

Symptomatic treatment for colds, nasal congestion, acute and chronic rhinitis, seasonal (hay fever) and perennial allergic rhinitis, acute and chronic sinusitis, vasomotor rhinitis. additional therapy for acute otitis media.

Preparation for surgery in the nasal area and elimination of edema of the nasal mucosa and paranasal sinuses after surgery.

Application

Before administering the preparation, you should thoroughly clean the nose.

Nasal drops. Children under the age of 1 year (as recommended by a doctor): 1 drop in each nasal passage 3-4 times a day.

Children aged 1 to 6 years: 1-2 drops in each nasal passage 3-4 times a day.

Adults and children over the age of 6: 3-4 drops in each nasal passage 3-4 times a day.

The duration of treatment should not exceed 7 days and depends on the course of the disease.

Contraindications

Hypersensitivity to any component of the preparation; the preparation, due to the content of phenylephrine, is contraindicated in atrophic rhinitis, as well as in patients taking MAO inhibitors, or taking them for the previous 14 days.

The preparation in the form of a gel and a spray is not recommended for children under 6 years of age. It is not recommended to take Vibrocil during pregnancy and lactation.

Side effects

The preparation is usually well tolerated. in some cases, mild and transient local reactions from the nasal mucosa (burning sensation or dryness) are possible. very rare: the development of allergic reactions (in particular local from the skin, itching of the body, swelling of the eyelids, face, general weakness).

Special instructions

Vibrocil should not be used for more than 1 week. prolonged or excessive use of the preparation can cause tachyphylaxis and a rebound effect (rhinitis medicamentosa).

As with the use of other vasoconstrictor agents, the recommended dose of the preparation should not be exceeded. Excessive use of Vibrocil, especially in children and the elderly, can cause manifestations of the systemic effect of the preparation.

Care should be taken to prescribe the preparation to patients with cardiovascular diseases, patients with hypertension, thyroid diseases and people with angle-closure glaucoma.

During pregnancy and breastfeeding. The preparation is not prescribed.

Children. Vibrocil in the form of drops in children under the age of 1 year is used only as directed by a doctor.

Influence on the ability to drive vehicles and work with mechanisms. Does not affect.

Interactions

The preparation is contraindicated in patients taking MAO inhibitors or taking them in the previous 14 days

Vasoconstrictor preparations should be used with caution in patients taking tricyclic antidepressants and antihypertensive preparations such as β-adrenergic receptor blockers.

Overdose

In case of accidental oral administration of the preparation to young children, no serious side effects have been reported.

Most cases were asymptomatic; very rarely, fatigue, stomach pain, mild tachycardia, increased blood pressure, agitation, insomnia, pallor of the skin were reported.

Treatment: the use of activated carbon, possibly laxatives in young children (gastric lavage is not required); adults and older children are prescribed plenty of fluids.

Storage conditions

In a place protected from light and heat; drops, gel - at a temperature not exceeding 30 ° C.