2 x VISINE (TETRYZOLINE) EYE DROPS 15ML - MADE IN BELGIUM - FREE SHIPPING

(VISINE (TETRYZOLINE) )
2 x VISINE (TETRYZOLINE) EYE DROPS 15ML - MADE IN BELGIUM - FREE SHIPPING
Availability: In Stock
Janssen Brand: Janssen

Composition

active substance: tetrahydrozoline hydrochloride;

1 ml of solution contains 0.5 mg of tetrahydrozoline hydrochloride

Excipients: benzalkonium chloride, sodium chloride, boric acid, sodium tetraborate, disodium edetate, purified water.

Release form

Eye drops, solution (15 ml in a bottle, equipped with a dropper and a screw cap, with protection from children. 1 bottle in a cardboard box).

pharmachologic effect

Pharmacodynamics

Tetrizoline is a sympathomimetic agent that belongs to the group of imidazoline decongestants. It directly stimulates the alpha-adrenergic receptors of the sympathetic nervous system with little or no influence from the beta-adrenergic receptors. When applied topically on the conjunctival mucosa, the preparation has a temporary vasoconstrictor effect on small blood vessels, thereby reducing vasodilation and conjunctival edema.

Pharmacokinetics

In a study involving 10 healthy volunteers after therapeutic ocular administration, tetrizoline was shown in blood serum and urine. The serum half-life of tetrizoline was approximately 6:00. Systemic absorption in patients varied, with maximum serum concentrations ranging from 0.068 to 0.380 ng / ml. After 24 hours, all patients were found to have tetrizoline in the urine.

Indications for use

Symptomatic temporary relief of secondary ocular hyperemia due to moderate irritation and allergic conjunctivitis.

Contraindications

Hypersensitivity to preparation components

Glaucoma.

Method of administration and dosage

For topical use in ophthalmology only.

The solution can be used for more than 72 hours only under medical supervision.

Adults and children ≥ 6 years of age

Instill 1-2 drops of the solution into the affected eye (s) up to 4 times a day.

Overdose

When using the preparation as recommended, overdose is unlikely.

If the preparation is swallowed, the treatment consists of taking activated charcoal and releasing the stomach. Further treatment should be symptomatic and supportive.

Side effects

Very rarely (<0.01%), adverse reactions associated with the use of tetrahydrozoline hydrochloride were observed in the post-registration period:

Reactions at the site of application (including burning in the eyes and periocular area, irritation of the mucous membrane of the eyes, pain in the eyes, itching, erythema, pain in the eyes, dilated pupils (mydriasis), reactive hyperemia of the eye ("rebound" redness of the eye)).

Systemic sympathomimetic effects can sometimes occur.

Allergic reactions may occur in patients with hypersensitivity to the components of the preparation.

special instructions

Use during pregnancy and lactation

Before using the preparation for pregnant and lactating women, it is recommended to consult a doctor to assess the possible risk.

Children

Use in children aged 2 to 6 years as directed by a doctor. There is no experience of using the preparation in children under 2 years of age.

The ability to influence the reaction rate when driving motor transport or other mechanisms

Eye drops can cause temporary blurred vision.

Interaction with other medicinal products and other forms of interaction

There are no known significant interactions with other preparations. Consult a doctor before using with other ophthalmic medications.

Storage conditions

Store in its original packaging at a temperature not exceeding 30 ° C, out of the reach of children.

The shelf life is 3 years. An open bottle should be used for no more than 4 weeks.

Tags: VISINE

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