Acnestop 200mg/g 30 g — Made in Ukraine — Free Delivery

The frequency of adverse reactions was determined according to meddra: very often (≥1 / 10); often (from? 1/100 to 1/10); infrequently (from ≥1 / 1000 to 1/100); rarely (from? 1/10 000 to 1/1000), very rarely (1/10 000), the frequency is unknown (cannot be estimated from the available data).

On the part of the skin and subcutaneous tissue: infrequently - seborrhea, acne, skin depigmentation; rarely - cheilitis (inflammation of the lips), rashes.

Local disorders: very often - burning, itching and erythema; often - peeling, pain, dryness, discoloration of the skin and irritation at the site of application; infrequently - paresthesia, dermatitis, discomfort and swelling at the site of application; single - urticaria, ulcer at the site of application; rarely - vesicles, eczema, a feeling of warmth and an ulcer at the site of application. Local skin irritations usually disappear with treatment.

From the immune system: rarely - hypersensitivity.

Cases of exacerbation of asthma symptoms have been reported in patients using azelaic acid (frequency unknown).

You should inform your doctor about the occurrence of any undesirable effects, including those not indicated in the instructions.

Tolerance for topical application of the preparation  in children aged 12 years and older is similar to that in adults.

Designed exclusively for external use. it is not allowed to get the cream in the eyes, mouth or mucous membranes. in case of accidental contact with eyes, mouth and other mucous membranes, rinse immediately with plenty of water. if eye irritation persists, it is recommended to seek medical attention. hands should be washed after each application of the cream.

The simultaneous use of cosmetic products, alcoholic or aggressive detergents, tinctures, astringents or abrasives or exfoliating agents should be limited during treatment as much as possible.

Benzoic acid may cause mild irritation to the skin, eyes and mucous membranes. Propylene glycol can also irritate the skin.

In rare cases, during post-registration observation, an exacerbation of asthma was reported in patients who used azelaic acid.

Use during pregnancy and lactation. Pregnancy. There have been no adequate and well-controlled studies of azelaic acid topical preparations in pregnant women. Animal studies do not indicate direct or indirect harmful effects on pregnancy, embryo / fetal development, childbirth or postnatal development. In pregnant women, the preparation should be used with caution.

Lactation. It is not known whether azelaic acid is excreted in breast milk in vivo. However, an in vitro experiment has demonstrated that the active substance can pass into breast milk. As expected, the distribution of azelaic acid in breast milk cannot lead to significant changes in relation to its baseline level, since it is not concentrated in breast milk and less than 4% of the topically applied azelaic acid is absorbed systemically (without increasing the endogenous exposure of the specified substance above the physiological level ). However, in women who are breastfeeding, the preparation should be used with caution.

Avoid contact of the infant with the skin / breast treated with the preparation.

Children. Used in adolescents from 12 years old. When using Aknestop cream in children aged 12 years and older, dose adjustment is not required. The safety and efficacy of Aknestop cream in children under 12 years of age have not been established.

The ability to influence the reaction rate when driving and working with other mechanisms. Does not affect.

Interaction studies have not been conducted.

During controlled clinical trials, preparation interactions were not observed.