Amizon Max 0.5g 10 capsules — Made in Ukraine — Free Delivery

Pharmacological properties

Pharmacodynamics. Amizon is a derivative of isonicotinic acid. It has an inhibitory effect on influenza viruses, has interferonogenic properties, increases the body's resistance to viral infections, has anti-inflammatory, antipyretic and analgesic effects.

The antiviral effect of amizone is associated with its direct effect on the hemagglutinins of the influenza virus, as a result of which the virion loses its ability to attach to target cells for further replication.

The anti-inflammatory effect is the result of stabilization of cell and lysosomal membranes, slowing down the degranulation of basophils, antioxidant action, normalization of the level of prostaglandins, cyclic nucleotides and energy metabolism in the focus of inflammation. The antipyretic properties of this agent are due to the effect on the thermoregulatory centers of the brain. The analgesic effect of the зкузфкфешщт is carried out through the reticular formation of the brain stem.

Amizon enhances persistent immunity by increasing the level of endogenous interferon in blood plasma by 3-4 times, lysozyme and increasing the titer of antibodies to infectious agents, as well as cellular - by stimulating the functional activity of T-lymphocytes and macrophages. This agent is a powerful inducer of endogenous interferon.

Pharmacokinetics. After oral administration, amizone quickly enters the bloodstream, Cmax in the blood is observed 2–2.5 hours after administration. T½ = 13.5-14 hours, metabolized in the liver, but rapidly excreted from tissues (T½ = 2-3 hours). It is excreted from the body by 90–95% in the urine in the form of metabolites.

Indications

Flu and ARVI treatment.

Application

Amizon max is taken orally after meals, without chewing.

Adults are prescribed 1 capsule 2–4 times a day for 5–7 days.

The maximum single dose is 1 g, the daily dose is 2 g.

Contraindications

Hypersensitivity to iodine preparations and other components of the preparation. The presence of allergic reactions, regardless of the nature of the allergen in the history. severe organic damage to the liver and kidneys.

Side effects

Allergic reactions: hypersensitivity reactions, including skin rashes, urticaria, angioedema, itching;

• from the digestive system: dryness and bitterness in the mouth, swelling of the oral mucosa, hypersalivation, yellowing of the tongue, nausea, vomiting, heartburn, abdominal pain, heaviness in the right hypochondrium, diarrhea, bloating;
• from the respiratory system: shortness of breath, burning sensation in the throat;
• others: headache, dizziness, weakness, fluctuations in blood pressure.

Special instructions

Care should be taken to prescribe the preparation to patients with thyroid disease, especially with hyperthyroidism.

Use during pregnancy and lactation. The preparation is contraindicated for use in the first trimester of pregnancy. Application in the II and III trimester is possible only as directed by a doctor. There are no data on the use of the preparation in women who are breastfeeding.

Children. The preparation in this dosage form is not used in children.

The ability to influence the reaction rate when driving or working with other mechanisms. Taking the preparation Amizon Max does not affect the ability to drive vehicles and work with other mechanisms.

Interactions

Amizon max enhances the effect of antibacterial and immunomodulatory agents. the combination of this preparation with ascorbic acid and other vitamins is advisable. also amizon max can be administered simultaneously with the use of recombinant interferon.

Overdose

Cases of overdose of amizone max have not been reported. in case of an overdose, an increase in the manifestations of side reactions is possible: staining of the mucous membrane in brown, reflex vomiting, abdominal pain and diarrhea. development of edema, erythema, acne-like and bullous eruptions, fever is possible.

Treatment: gastric lavage, symptomatic treatment.

Storage conditions

In a dry, dark place at a temperature not exceeding 25 ° C.