Barboval 2p x 30 capsules — Made in Ukraine — Free Delivery
(Barboval)
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Description Barboval 2p x 30 capsules — Made in Ukraine — Free Delivery
Indication
Neuroses accompanied by increased excitability, insomnia; hysteria; as part of the complex treatment of mild attacks of angina pectoris, angina pectoris in the initial stage; tachycardia of functional genesis; with spasms of the stomach and intestines, flatulence.
Application
Barboval is taken orally. adults usually take 1-2 capsules 2-3 times a day for 10-15 days. it is better to take the preparation 20-30 minutes before meals. after a break of 10-15 days, the course of treatment can be repeated. the maximum daily dose is 6 capsules.
Contraindication
Hypersensitivity to any components of the preparation, liver and kidney failure, hepatic porphyria, severe arterial hypotension, acute myocardial infarction, severe heart failure, diabetes, depression, myasthenia gravis, alcoholism, preparation and medication addiction, respiratory diseases with shortness of breath, obstructive syndrome . the preparation should not be used in children, pregnant and lactating women.
Side effects
Usually the preparation is well tolerated. the development of the following adverse reactions is possible:
- from the side of the digestive system: constipation, a feeling of heaviness in the epigastric region, with long-term use - impaired liver function, nausea, vomiting;
- from the nervous system: weakness, ataxia, impaired coordination of movements, nystagmus, hallucinations, paradoxical excitement, decreased concentration of attention, fatigue, slowing of reactions, headache, cognitive impairment, confusion, drowsiness, light dizziness;
- from the hematopoietic organs: anemia, thrombocytopenia, agranulocytosis;
- from the side of the cardiovascular system: arterial hypotension, bradycardia;
- from the immune system: hypersensitivity reactions, including angioedema, allergic reactions, including skin rashes, itching, urticaria;
- from the skin and mucous membrane: Stevens-Johnson syndrome, toxic epidermal necrolysis;
- from the musculoskeletal system: with long-term use of products containing phenobarbital, there is a risk of osteogenesis disorder;
- other: difficulty breathing.
Long-term use of preparations containing bromine can lead to bromine poisoning, which is characterized by the following symptoms: CNS depression, depressed mood, confusion, ataxia, apathy, conjunctivitis, rhinitis, lacrimation, acne or purpura.
Special instructions
The presence of phenobarbital in the medicinal product can lead to the risk of developing Stevens-Johnson syndrome and Lyell's syndrome, which is most likely in the first weeks of treatment. long-term use is not recommended due to the risk of preparation addiction, possible accumulation of bromine in the body and the development of bromine poisoning. in cases where the pain in the heart area does not go away after taking the preparation, it is necessary to consult a doctor to rule out acute coronary syndrome. the preparation should be prescribed with caution in decompensated heart failure, hypotension, hyperkinesis, hyperthyroidism, hypofunction of the adrenal glands, acute and constant pain, acute preparation intoxication.
Castor oil, which is part of the preparation, can cause stomach upset and diarrhea.
The preparation contains lactose, so patients with rare hereditary forms of galactose intolerance, lactase deficiency or glucose-galactose malabsorption syndrome should not use the preparation.
Use during pregnancy and breastfeeding. The preparation should not be used in women during pregnancy and breastfeeding.
Children. There is no experience of using the preparation to treat children, so they are used in pediatric practice.
The ability to influence the speed of reaction when driving a motor vehicle or working with other mechanisms. The preparation can cause drowsiness and dizziness, therefore, during treatment, patients are not recommended to work with dangerous mechanisms and drive vehicles.
Interactions
Simultaneous use with neuroleptics and tranquilizers potentiates, and with stimulants of the central nervous system - weakens the effect of each component of the preparation. barboval, containing derivatives of barbituric acid, enhances the effect of local anesthetics, pain relievers and hypnotics. alcohol enhances the effects of the preparation and can increase its toxicity. the effect of the preparation increases against the background of the use of valproic acid preparations. the presence of phenobarbital in the composition of Barboval can induce liver enzymes, and this makes its simultaneous use with preparations metabolized in the liver undesirable (with coumarin derivatives - indirect anticoagulants, griseofulvin, glucocorticoids, oral contraceptives, cardiac glycosides, antimicrobial, antiviral, antifungal, antiepileptic , anticonvulsant, psychotropic, oral hypoglycemic, hormonal, immunosuppressive, cytostatic, antiarrhythmic, antihypertensive preparations), as their effectiveness will decrease as a result of a higher level of metabolism.
MAO inhibitors prolong the effect of phenobarbital. Rifampicin may reduce the effect of phenobarbital.
With the simultaneous use of phenobarbital with gold preparations, the risk of kidney damage increases.
With long-term use of phenobarbital with NSAIDs, there is a risk of stomach ulcers and bleeding.
Simultaneous use of phenobarbital with zidovudine increases the toxicity of both preparations.
The preparation increases the toxicity of methotrexate. Alcohol should be avoided while taking the preparation.
Overdose
With long-term or frequent use, preparation accumulation may occur, which leads to clinical manifestations of overdose, namely:
- Manifestations of chronic bromine poisoning are depression, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis, impaired movement coordination. Symptomatic therapy is prescribed to eliminate these manifestations.
Continuous long-term use of the preparation can cause addiction, preparation dependence, withdrawal syndrome, and sudden cessation of use - withdrawal syndrome. Long-term use of the preparation is sometimes accompanied by increased psychodynamic activity instead of the expected sedation.
Symptoms of overdose: suppression of breathing, until it stops; depression of the central nervous system, up to coma; suppression of cardiovascular activity, including rhythm disturbances, lowering of blood pressure, up to a collaptoid state; nausea, weakness, decrease in body temperature, decrease in diuresis.
Storage conditions
At a temperature not higher than 25 °C.
Tags: Barboval
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