Biolectra Magnesium Forte, 10 effervescent tablets — Made in Germany — Free Delivery
(Biolectra Magnesium Forte)
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Description Biolectra Magnesium Forte, 10 effervescent tablets — Made in Germany — Free Delivery
Pharmacological properties
Magnesium is an essential element for the body's metabolism. it is necessary to ensure many energy processes, is involved in the metabolism of proteins, fats, carbohydrates, nucleic acids and in the process of neuromuscular excitation.
Numerous functions of energy generation or expenditure (for example, oxidative phosphorylation or ion pump, muscle contraction) depend on magnesium, and if it is deficient, they can be partially or completely impaired.
Magnesium activates glycolytic enzymes, cellular oxidation enzymes, nucleic acid synthesis enzymes, it also plays an important role in the processes of myocardial contraction, is a fibrinogen and platelet stabilizer. It is known that magnesium deficiency is one of the reasons for the development of hypertension, vasospasm, neoplastic diseases and urolithiasis. In stressful situations, an increased amount of free ionized magnesium is excreted, so the additional amount of magnesium contributes to an increase in stress resistance. Magnesium plays a leading role in the processes of neuromuscular excitation, acting as an antagonist of calcium ions.
The total amount of magnesium in the body of an adult is about 20–30 g. Of this amount, about 50% is contained in bones, 45% in cells, and only 5% of the total amount can be determined in blood plasma.
The intracellular concentration of magnesium varies from 10 to 60 mmol / L, the normal value of the concentration of magnesium in the blood plasma is in the range from 0.7 to 1.1 mmol / L. In blood plasma, approximately ⅔ of magnesium ions are in dissolved form and about 1/3 binds to proteins.
When taken internally, magnesium is absorbed depending on the original magnesium content in the body. With a deficiency of magnesium in the body, more of it is absorbed, and with saturation with magnesium, less. The resorption ratio corresponds to the homeostatically controlled resorption kinetics characteristic of physiologically active substances.
With an equilibrium balance of magnesium and normal kidney function, even with high doses of magnesium, its accumulation does not occur, exceeding the normal limit.
After absorption in the intestine, magnesium is mainly excreted by the kidneys. Undigested magnesium is excreted in the feces.
Indications
Treatment and prevention of magnesium deficiency in the body in cases where it is the cause of muscle disorders (neuromuscular disorders, convulsions), with chronic physical and mental fatigue, irritability, myalgia, with intense physical and mental stress, during pregnancy. hypomagnesemia resulting from prolonged smoking and alcohol abuse, prolonged use of laxatives, contraceptives, certain diuretics, or as a result of osmotic diuresis in patients with diabetes mellitus with persistent hyperglycemia.
Application
The dose of biolectra magnesium forte depends on the degree of magnesium deficiency in the body. the average daily dose is 1–2 effervescent tablets (243–486 mg of magnesium ions = 10–20 mmol).
Children over the age of 6 are prescribed 1 effervescent tablet 1 time per day.
Adults and adolescents are prescribed 1 effervescent tablet 1-2 times a day.
With a severe degree of magnesium deficiency, the doctor may prescribe the preparation Biolectra Magnesium Forte in higher doses.
The tablet must be dissolved in a glass of water, the resulting solution should be drunk.
The duration of treatment depends on the underlying causes of the magnesium deficiency.
Long-term magnesium intake in high doses should be supervised by a physician.
Contraindications
Hypersensitivity to the components of the preparation. the preparation is not recommended for use in case of impaired renal function and impaired conduction of excitation in the heart (high av-blockade), which can lead to bradycardia. it is necessary to check whether there are violations of mineral and electrolyte metabolism (hypermagnesemia, hyperkalemia). the preparation biolectra magnesium forte is contraindicated in severe myasthenia gravis, exicosis and calcium-magnesium-phosphate-ammonium diathesis.
Side effects
At higher doses, mild diarrhea is possible, which is not considered dangerous and disappears when the dose is reduced. long-term use of the preparation biolectra magnesium forte in high doses may cause fatigue. in this case, the physician must, on the basis of clinical and laboratory studies, decide on the advisability of further use of magnesium.
special instructions
1 effervescent tablet contains 7.35 mmol (169 mg) sodium. this should be considered in patients on a low sodium / salt diet.
1 effervescent tablet contains 3.48 mmol (136 mg) potassium. This should be taken into account in patients with impaired renal function, as well as those on a diet low in potassium.
Use during pregnancy and lactation. During pregnancy and lactation, there are no risks of using the preparation.
Children. The preparation is not recommended for use in children under 6 years of age.
The ability to influence the reaction rate when driving or working with other mechanisms. Does not affect.
Interactions
With the simultaneous use of iron, sodium fluoride or tetracycline, the absorption of iron, sodium fluoride, tetracycline and magnesium may be impaired. in such cases, between taking the preparation biolectra magnesium forte and iron preparations, sodium fluoride, tetracycline, an interval of 3-4 hours must be observed.
With the simultaneous administration of preparations containing aluminum (for example, antacids), the absorption of aluminum may increase.
Strengthens the effect of antiarrhythmic, antihypertensive preparations, reduces the degree of magnesium deficiency and the risk of associated complications when taking diuretics, aminoglycosides, cisplatin, cyclosporine, amphotericin, methotrexate, laxatives.
Overdose
When magnesium salts are used internally, hypermagnesemia occurs only with renal failure. magnesium salts are contraindicated in these patients.
Intoxication symptoms. High concentrations of magnesium cause relaxation of skeletal muscles (plasma magnesium concentration 5.5 mmol / l). The concentration of magnesium ions of 10–20 mmol / l lengthens the conduction period in the heart, and even higher concentrations lead to cardiac arrest in diastole.
Treatment for intoxication. The intravenous administration of calcium instantly leads to the relief of the described symptoms, since there is an antagonism between calcium and magnesium ions.
Storage conditions
In its original packaging at a temperature not exceeding 25 ° C.
Tags: Biolectra
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