Biseptol 400mg/80mg, 2p x 20 tablets — Made in Poland by Adamed — Free Delivery
Coupon code -5%: BONUS23
You can apply the coupon in the shopping cart at checkout.
Description Biseptol 400mg/80mg, 2p x 20 tablets — Made in Poland by Adamed — Free Delivery
Product description
Biseptol tablets are used to treat infections caused by pathogenic microorganisms sensitive to the preparation, in cases where the benefit from such treatment outweighs the possible risk (it is necessary to decide whether only one antibacterial agent can be used):
- infections of the ENT organs and respiratory tract: sinusitis, otitis media, acute and chronic bronchitis, bronchiectasis, pneumonia (including those caused by Pneumocystis carinii), pharyngitis, tonsillitis (in infections caused by group A β-hemolytic streptococci, the frequency of eradication is not quite sufficient );
- infections of the kidneys and urinary tract: acute and chronic cystitis, pyelonephritis, urethritis, prostatitis, chancre;
- digestive tract infections: typhoid and paratyphoid fever, shigellosis (caused by susceptible strains of Shigella flexneri and Shigella sonnei, if antibiotic therapy is indicated), "traveler's" diarrhea caused by enterotoxic strains of Escherichia coli, cholera (in addition to fluid and electrolyte recovery);
- other bacterial infections: acute and chronic osteomyelitis, brucellosis, nocardiosis, actinomycosis, toxoplasmosis, South American blastomycosis.
Compound
Active ingredients: sulfamethoxazole, trimethoprim (co-trimoxazole);
1 tablet 100 mg / 20 mg contains 100 mg sulfamethoxazole, 20 mg trimethoprim;
1 tablet 400 mg / 80 mg contains sulfamethoxazole 400 mg trimethoprim 80 mg;
Excipients: potato starch, talc, magnesium stearate, polyvinyl alcohol.
Contraindications
- hypersensitivity to trimethoprim and sulfamethoxazole (including sulfonamide derivatives, sulfonylurea antidiabetic agents, and thiazide diuretics) and other components of the preparation;
- acute hepatitis, liver dysfunction, severe liver failure, including diagnosed damage to the liver parenchyma, porphyria;
- blood diseases, hematopoietic disorders, severe hematological disorders, megaloblastic anemia caused by folic acid deficiency, glucose-6-phosphate dehydrogenase deficiency (threat of hemolysis);
- severe renal failure, which is characterized by creatinine clearance less than 15 ml / minute, if it is not possible to determine the concentration of the preparation in the blood plasma (except in cases of hemodialysis);
- the preparation is contraindicated in patients undergoing chemotherapy;
- the preparation should not be administered in combination with dofetilide.
Mode of application
Adults and children over 12 years old. The usual starting dose is two tablets 2 times a day (morning and evening). The tablets should be taken after meals with plenty of liquid. In severe infections, higher daily doses can be prescribed - up to 3 tablets 2 times a day. For maintenance therapy lasting more than 14 days, it is recommended to take one tablet 2 times a day.
Children 6-12 years old. The recommended daily dose for children is 6 mg of trimethoprim and 30 mg of sulfamethoxazole per kg of body weight. This dose should be divided into two doses.
The recommended daily dose for children aged 6 to 12 years is one tablet 2 times a day.
Duration of treatment: for acute infections, with the exception of gonorrhea, treatment should be continued for at least 5 days or 2 more days after the symptoms of the disease disappear. A three-day course of treatment may be sufficient for women with uncomplicated acute cystitis. However, children with this disease are recommended to use the preparation for 5-7 days.
Application features
Pregnant
This preparation should not be used during pregnancy and lactation.
Children
The preparation is used to treat children over 6 years old.
Drivers
The preparation does not cause a decrease in psychophysical activity and the ability to drive vehicles and maintain mechanisms. If during treatment, side effects from the nervous system (dizziness, headache, convulsions, nervousness, feeling of fatigue) develop, which can cause a decrease in the speed of psychomotor reactions, you should avoid driving and working with complex mechanisms.
Overdose
It is not known what dose of the preparation can be life-threatening. In case of an overdose of sulfonamides, there is a lack of appetite, colicky pain, nausea, vomiting, diarrhea, dizziness, headache, drowsiness, loss of consciousness. Fever, hematuria and crystalluria may appear, with chronic overdose, bone marrow suppression and hepatitis may develop. In acute overdose of trimethoprim, nausea, vomiting, dizziness, headache, mental depression, confusion, and bone marrow suppression may occur.
If symptoms of an overdose appear, it is necessary to stop using the preparation, induce vomiting, take a large amount of liquid, if the urine output is insufficient, and the kidney function is normal. Acidification of urine will speed up the elimination of trimethoprim, but increase the risk of sulfonamide crystallization in the kidneys. The blood picture, serum electrolytes and other biochemical parameters of the patient should be monitored. If bone marrow damage or symptoms of hepatitis develop, the usual treatment should be applied. Hemodialysis is ineffective. Peritoneal dialysis is ineffective.
In chronic poisoning, inhibition of the function of the spinal cord is observed, manifesting thrombocytopenia, leukopenia, or megaloblastic anemia. In this case, leucovorin should be used (5-15 mg per day).
Side effects
The most common adverse reactions during preparation treatment are from the digestive tract (nausea, vomiting, lack of appetite) and allergic skin reactions (rash, urticaria).
Interaction
Zidovudine: In some cases, the simultaneous use of co-trimoxazole and zidovudine increases the risk of hematological disorders caused by Biseptol. If the simultaneous use of co-trimoxazole and zidovudine is necessary, blood counts should be monitored.
Folinic acid has been shown that the additional use of folic acid affects the antimicrobial efficacy of trimethoprim-sulfamethoxazole. This has been observed in the prevention and treatment of pneumocystis jiroveci pneumonia.
Storage conditions
Store at a temperature not exceeding 25 ° C.
Keep out of the reach of children.
The shelf life is 5 years.
Tags: Biseptol
Buyers Online
- Customer from Nazilli placed a new order for BIOSTERON 25 MG 60 TABS — MADE IN POLAND — FREE SHIPPING
- Customer from Nazilli registered for an account
- Customer placed a new order for Duodart 0.5mg/0.4mg, 30 capsules — Made in Germany — Free Delivery
- Customer from Midlothian placed a new order for STIMULOTON 50MG 30 PILLS — MADE IN HUNGARY — FREE SHIPPING
- Customer from Midlothian logged in
- Customer from Cleveland logged in
- Customer from Montreal logged in
- Customer from Hopwood registered for an account
- Customer placed a new order for Estramon 50, transdermal patch 50 mcg/day, 6pcs — Made in Germany — Free Delivery
- Customer from Gloucester placed a new order for WAX Pilomax Tricho, strengthening shampoo against hair loss, 200 ml — Made in Poland — Free Delivery and 2 more products
- Customer from Gloucester registered for an account
- Customer from Cary placed a new order for INFECTVAGIN VAGINAL GLOBULES 10 PIECES — MADE IN POLAND — FREE SHIPPING
- Customer from Cary logged in
- Customer from Guyton placed a new order for Paroxin 20mg 60 tablets — Made in Ukraine — Free Delivery
- Customer from Guyton logged in
- Customer from Montreal placed a new order for 4 x ESSENTIALE FORTE 50 CAPS - MADE IN POLAND - FREE SHIPPING and 1 more product
- Customer placed a new order for Combispasm 100 tablets — Made in India — Free Delivery
- Customer from Montreal registered for an account
- Customer from Philadelphia placed a new order for L-Thyroxin 100 Berlin-Chemie 2p x 50 tablets — Made in Germany — Free Delivery
- Customer from Philadelphia registered for an account