Biseptol 480 concentrate for the preparation of solution for infusion 80 mg + 16 mg in ampoules of 5 ml 10 pcs — Made in Poland — Free Delivery

Treatment. In the event of an established, suspected or accidental overdose, the preparation should be discontinued immediately. Increased renal excretion by forced diuresis (alkalinization of urine promotes the elimination of sulfamethoxazole), hemodialysis (peritoneal dialysis is ineffective). It is necessary to monitor the blood picture and the level of electrolytes. With pronounced pathological changes in the blood picture or jaundice, prescribe specific treatment. To eliminate the effect of trimethoprim on hematopoiesis, calcium folinate can be prescribed at a dose of 3-6 mg for 5-7 days.

Use during pregnancy or lactation

There are no reliable data regarding the use of co-trimaxozole in pregnant women. Studies have shown a possible link between the action of folate antagonists and the development of fetal damage. Trimethoprim is a folic acid antagonist, in animal studies, both active ingredients caused fetal abnormalities.

Co-trimaxozole should not be used during pregnancy, especially in the first trimester, unless absolutely necessary. If necessary, pregnant women should consider the use of folic acid.

Sulfamethoxazole competes with bilirubin for the binding site with blood plasma albumin. If the preparation was used by the mother immediately before childbirth, significant concentrations of the preparation obtained from the mother's body are stored in the newborn for several days, and there is a risk of bilirubin deposition or increased hyperbilirubinemia, which is theoretically associated with the risk of developing kernicterus. This is especially true for newborns with an increased risk of developing hyperbilirubinemia, especially in premature babies and in children with glucose-6-phosphate dehydrogenase deficiency.

Breastfeeding.

Since trimethoprim and sulfamethoxazole pass into breast milk, breastfeeding while taking Biseptol 480 is not recommended, especially for children with hyperbilirubinemia or at risk of developing it.

In addition, the use of co-trimaxozole in infants younger than 8 weeks should be avoided, given the tendency to develop neonatal hyperbilirubinemia.

For use in children over 6 weeks of age.

The ability to influence the reaction rate when driving or driving other mechanisms

Biseptol 480 usually does not directly affect the ability to drive vehicles or work with other mechanisms. However, there is a possibility of side effects from the nervous system and psyche that can affect this ability, in some cases - to a large extent.

active ingredients: sulfamethoxazolum, trimethoprimum;

1 ml of concentrate contains 80 mg sulfamethoxazole, 16 mg trimethoprim

Excipients: propylene glycol, ethanol 96%, benzyl alcohol, sodium metabisulfite (E 223), sodium hydroxide, sodium hydroxide 10%, water for injection

1 ampoule (5 ml of concentrate) contains 400 mg of sulfamethoxazole and 80 mg of trimethoprim.

Store in its original packaging at a temperature not exceeding 25 ° C. Do not freeze.

Keep out of the reach of children.

The shelf life is 5 years.

Do not use after the expiration date.