Dermazole Plus (Ketoconazole) shampoo 100 ml — Made in India— Free Delivery
(Dermazole Plus)
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Description Dermazole Plus (Ketoconazole) shampoo 100 ml — Made in India— Free Delivery
Pharmacological properties
Pharmacodynamics. The pharmacological properties of the shampoo are due to the properties of the active substances included in its composition: ketoconazole and zinc pyrithione.
Ketoconazole - a synthetic derivative of imidazole dioxalan, has a fungicidal, fungistatic effect against dermatophytes (Epidermophyton spp., Microsporum spp., Trichophyton spp.), Yeast and yeast-like fungi of different strains (Candida spp., Malassezia - Purgatory furfum.
Zinc pyrithione, when applied externally, has antimicrobial and antifungal effects; effective against streptococci, staphylococci, fungi and a number of other pathogenic microorganisms. Zinc pyrithione is responsible for the anti-seborrheic effect of the preparation and acts against dandruff. Ketoconazole shampoo reduces the flaking and itching associated with dandruff, seborrheic dermatitis and pityriasis.
Aloe Vera powder helps moisturize hair, enrich it with vitamins and microelements.
Pharmacokinetics. Special studies of the pharmacokinetics of shampoo have not been carried out, but it is known that ketoconazole and zinc pyrithione, when applied externally, are practically not absorbed into the systemic circulation and do not cause systemic action.
Indications
Treatment and prevention of fungal diseases of the scalp, accompanied by scaling and itching, such as: dandruff, seborrheic dermatitis, local pityriasis versicolor of the scalp.
Application
Shampoo should be shaken well before use.
Shampoo should be applied to damp hair and scalp for 3-5 minutes, then rinse with water.
Recommended regimens for adults:
Contraindications
Hypersensitivity to ketoconazole, zinc pyrithione or any other component of the preparation.
Side effects
Skin and subcutaneous tissue disorders: erythema, burning sensation of the skin, itching, acne, contact dermatitis, skin irritation, rash, pustular rash at the site of application, urticaria, dry skin, increased skin peeling, discomfort, hypersensitivity, changes in the skin.
From the appendages of the skin: changes in the structure of the hair, increased dryness or oily hair, hair loss (alopecia), changes in hair color (in particular in patients with chemically damaged or gray hair), discoloration of the nails. There are cases of straightening naturally curly hair.
From the nervous system: taste disturbance (dysgeusia), paresthesia, hypersensitivity.
From the immune system: hypersensitivity reactions, including anaphylactoid reactions; angioedema.
From the side of the organ of vision: eye irritation, eyelid edema, increased lacrimation.
Infections and invasions: folliculitis.
Special instructions
The preparation is intended for external use only.
When using the preparation, avoid contact with eyes and mucous membranes.
In case of contact with eyes, rinse thoroughly with water.
Seborrheic dermatitis and dandruff are often accompanied by increased hair loss, which in some cases may continue for some time even at the beginning of shampoo use.
The preparation contains butylhydroxytoluene (E321), which can cause local skin reactions (eg contact dermatitis) or irritation of the eyes and mucous membranes.
Use during pregnancy and lactation. During pregnancy and lactation, the preparation can be used only in cases where the expected benefit to the mother outweighs the potential risk to the fetus / child.
Children. There is no experience of using the preparation in children.
The ability to influence the reaction rate when driving or working with other mechanisms. Does not affect.
Interactions
When prescribing dermazole plus to patients who have been treated with corticosteroids for local use for a long time, treatment with the latter should be continued and they should be canceled gradually within 2-3 weeks (in order to avoid withdrawal syndrome).
Given the absence of significant systemic absorption, interaction with other preparations is unlikely.
It is not recommended to use simultaneously with dermatological preparations containing GCS.
Overdose
Since the shampoo is intended for external use only and ketoconazole is practically not absorbed into the systemic circulation, the development of overdose symptoms is unlikely. if the shampoo is accidentally swallowed, only supportive and symptomatic measures are used. do not induce vomiting and gastric lavage to prevent aspiration.
Storage conditions
At a temperature not higher than 25 ° C.
Tags: Dermazole
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