Dioflan 500mg 60 tablets — Made in Ukraine — Free Delivery

Pharmacological properties

Pharmacodynamics. Dioflan has a venotonic and angioprotective effect, increases venous tone, reduces venous distensibility and venostasis, improves microcirculation, reduces capillary permeability and increases their resistance, improves lymphatic drainage, and increases lymphatic outflow. Dioflan also reduces the interaction of leukocytes and endothelium, adhesion of leukocytes in postcapillary venules, which reduces the damaging effect of inflammatory mediators on the walls and leaflets of the valves of the veins.

Pharmacokinetics. T½ is 11 hours. The active substance of the preparation  is excreted mainly through the intestines. On average, 14% of the dose taken is excreted in the urine.

Indications

Symptomatic treatment of venolymphatic insufficiency (edema, pain, heaviness in the legs). symptomatic treatment of hemorrhoids.

Application

For oral administration.

Treatment of venolymphatic insufficiency (symptoms: swelling, pain, heaviness in the legs, night cramps, trophic ulcers, lymphedema). The recommended dose is 2 tablets per day: in the morning and in the evening with meals. After a week of use, you can take 2 tablets once a day with meals.

Treatment of chronic hemorrhoids. 2 tablets per day (in 2 divided doses) with meals. After a week of use, you can take 2 tablets per day, once with meals.

Treatment of acute hemorrhoids: 6 tablets per day for the first 4 days and 4 tablets per day for the next 3 days. Apply with meals. Divide the daily number of tablets into 2-3 doses.

A course of treatment. The duration of treatment depends on the indications for use and the course of the disease. The average duration of treatment is 2-3 months.

Contraindications

A history of hypersensitivity to the active substance or any of the components of the preparation.

Side effects

Neurological disorders: dizziness, headache, malaise.

From the digestive system: diarrhea, dyspepsia, nausea, vomiting, colitis.

Skin and subcutaneous tissue disorders: rash, itching, urticaria, isolated edema of the face, lips, eyelids, Quincke's edema.

The presence of the yellow sunset FCF (E110) in the composition of the preparation may cause allergic reactions.

Special instructions

The use of this preparation for acute hemorrhoids does not replace specific treatment and does not interfere with the treatment of other proctological diseases. if the symptoms do not disappear quickly during a short course of treatment, a proctological examination should be carried out and the therapy should be revised.

In case of venous circulation disorders, more effective treatment is provided by a combination of therapy in compliance with the following lifestyle recommendations:

avoid prolonged exposure to the sun, on legs, overweight;

walking and, in some cases, wearing special stockings to improve blood circulation.

Use during pregnancy and lactation. In pregnant women, the preparation should be used with caution. Before use, consult a doctor. Studies have not revealed a teratogenic effect of diosmin, hesperidin, and no side effects have been reported. Due to the lack of data on the penetration of the preparation  into breast milk, the use of the preparation during breastfeeding should be avoided. Reproductive toxicity studies have shown no effect of diosmin, hesperidin on rat fertility.

The ability to influence the reaction rate when driving vehicles or other mechanisms. The preparation does not affect the ability to drive vehicles and work with different mechanisms. In the event of signs of side effects of the preparation (see SIDE EFFECTS), care must be taken.

Children. There are no data on the use of the preparation in children.

Interactions

Interaction studies have not been conducted. there are no data on cases of interaction.

Overdose

No cases of overdose have been reported.

Storage conditions

In its original packaging at a temperature not exceeding 25 ° C.