Enalapril-Teva 20 mg 30 tablets — Made in Poland — Free Delivery

(Enalapril-Teva)
Enalapril-Teva 20 mg 30 tablets — Made in Poland — Free Delivery
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TEVA Brand: TEVA

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Description Enalapril-Teva 20 mg 30 tablets — Made in Poland — Free Delivery

Product description

Enalapril-Teva tablets are used for the following indications:
Treatment of arterial hypertension.
Treatment of clinically significant heart failure.
Prevention of clinically significant heart failure in patients with asymptomatic left ventricular dysfunction (ejection fraction ≤ 35%).

Structure

Active substance: enalapril maleate;
1 tablet contains 2.5 mg or 5 mg or 10 mg or 20 mg of enalapril maleate;
Excipients:
Tablets of 2.5 mg and 5 mg: lactose, corn starch, talc, sodium bicarbonate, hydroxypropyl cellulose, magnesium stearate;
Tablets of 10 mg and 20 mg: lactose, corn starch, talc, sodium bicarbonate, magnesium stearate, iron oxide red, iron oxide yellow (for tablets of 20 mg).

Contraindications

Hypersensitivity to enalapril, to any excipient or to any other ACE inhibitor.
A history of angioedema associated with the use of ACE inhibitors.
Hereditary or idiopathic angioedema.
Pregnant women or women planning to become pregnant.
Enalapril should not be used with drugs containing aliskiren in patients with diabetes mellitus or with impaired renal function (GFR <60 ml / min / 1.73 m 2).

Mode of application

Food intake does not affect the absorption of Enalapril-Teva tablets.
The dosage should be selected individually in accordance with the condition of each patient and the blood pressure response in response.

Application features

Pregnant
Contraindicated.
Children
For use in children from 6 years of age.
Enalapril is not recommended for newborns and children with a glomerular filtration rate <30 ml / min / 1.73 m 2 due to lack of data.
Drivers
When driving vehicles or other mechanisms, you should take into account the possible development of dizziness or increased fatigue.

Overdose

There are limited data regarding drug overdose. The main signs of an overdose, according to the available data, are severe arterial hypotension, which begins approximately 6 hours after the use of the drug and coincides with a blockade of the renin-angiotensin system, and stupor. Symptoms associated with an ACE inhibitor overdose may include circulatory shock, electrolyte imbalance, renal failure, hyperventilation, tachycardia, heart palpitations, bradycardia, dizziness, anxiety, and coughing. Plasma levels of enalaprilat in excess of 100 and 200 times the maximum levels achieved with therapeutic doses have been reported after administration of 300 mg and 440 mg of enalapril, respectively.
For the treatment of overdose, intravenous infusion of isotonic solution is recommended. When arterial hypotension occurs, the patient should be laid down in a horizontal position. Consideration may be given to the need for angiotensin II infusions and / or intravenous catecholamines. If the drug has been recently taken, measures to eliminate enalapril maleate are recommended (such as artificial vomiting, gastric lavage, the use of absorbents and sodium sulfate). Enalaprilat can be removed from the systemic circulation by hemodialysis (see section "Peculiarities of use": patients on hemodialysis). For bradycardia resistant to therapeutic agents, therapy with a pacemaker is indicated. Important vital signs, electrolyte concentrations and serum creatinine levels should be monitored continuously.

Side effects

When using enalapril, in most cases, side effects were minor, were temporary and did not require discontinuation of therapy.
From the blood system: anemia (including aplastic and hemolytic); neutropenia, decreased hemoglobin, decreased hematocrit, thrombocytopenia, agranulocytosis, bone marrow suppression, pancytopenia, lymphadenopathy, autoimmune diseases.
From the endocrine system: syndrome of impaired secretion of antidiuretic hormone.
Metabolic disorders: hypoglycemia (see section "Peculiarities of use").
From the nervous system and psyche: depression, headache; confusion, drowsiness, insomnia, nervousness, paresthesia, vertigo; sleep disorders, abnormal dreams.
From the side of the organs of vision: blurred vision.
On the part of the cardiovascular system: dizziness; hypotension (including orthostatic hypotension), syncope, chest pain, rhythm disturbance, angina pectoris, tachycardia; orthostatic hypotension, rapid heartbeat, myocardial infarction or stroke, possibly due to an excessive decrease in pressure in patients at high risk (see section "Peculiarities of use"), Raynaud's phenomenon.
From the respiratory system: cough; dyspnea; rhinorrhea, sore throat and hoarseness, bronchospasm / asthma; pulmonary infiltrates, rhinitis, allergic alveolitis / eosinophilic pneumonia.
From the digestive system: nausea; diarrhea, abdominal pain, change in taste; intestinal obstruction, pancreatitis, vomiting, dyspepsia, constipation, anorexia, stomach irritation, dry mouth, peptic ulcers; stomatitis / aphthous ulcers, glossitis; angioedema of the intestine.
From the hepatobiliary system: liver failure, hepatocellular or cholestatic hepatitis, hepatitis, including necrosis, cholestasis (including jaundice).
On the part of the skin and subcutaneous tissues: rash, hypersensitivity / angioedema of the face, extremities, lips, tongue, glottis and / or larynx (see section "Peculiarities of use"); increased sweating, itching, urticaria, alopecia; erythema multiple, Stevens-Johnson syndrome, exfoliative dermatitis, toxic epidermal necrolysis, pemphigus, erythroderma.
The development of a complex symptom complex was reported, which included some or all of the following manifestations: fever, serositis, vasculitis, myalgia / myositis, arthralgia / arthritis, a positive test for antinuclear antibodies, increased erythrocyte sedimentation rate (ESR), eosinophilia and leukocytosis. Rash, photosensitivity and other skin reactions can also occur as side effects.
From the urinary system: impaired renal function, renal failure, proteinuria; oliguria.
Reproductive system disorders: impotence; gynecomastia.
General violations and violations of the conditions of administration: asthenia; fatigue; muscle cramps, hot flashes, ringing in the ears, discomfort, fever.

Interaction

Alcohol enhances the hypotensive effect of ACE inhibitors.
Sympathomimetics may reduce the antihypertensive effects of ACE inhibitors.

Storage conditions

Keep out of the reach of children in its original packaging at a temperature not exceeding 25 ° C.
Shelf life is 3 years. 

Tags: Enalapril

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