Enterospasmyl 30 capsules — Made in Italy — Free Delivery

Pharmacological properties

Enterospasmyl is a combination preparation that includes the non-atropinic antispasmodic agent phloroglucinol dihydrate and simethicone, which prevents the accumulation of gases in the intestines.

After oral administration, phloroglucinol is rapidly absorbed and metabolized during the first passage through the liver, excreted from the body in the form of metabolites, mainly in the urine. The time to reach Cmax in plasma Tmax is 1 hour, with a Cmax value of 2.74 mg / ml T½ is 2 hours. Systemic bioavailability after oral administration is 30%. Clinical studies confirm the relaxing effect of gastrointestinal smooth muscle. Phloroglucinol dihydrate slows down the excess motility of the colon and colon, which typically occurs in response to food intake in patients with functional intestinal disorders.

Simethicone is a non-toxic, inert silicon-based surfactant that inhibits and breaks down gas bubbles. Due to the decrease in the surface tension of the liquid, Enterospasmyl causes the combination of gas bubbles in the gastrointestinal tract, which leads to dispersion and release of gas in a physiological way.

Simethicone prevents the formation of image defects that arise from gas bubbles during ultrasound or X-ray examinations.

It is not absorbed in the body, after passing through the gastrointestinal tract, it is excreted unchanged.

Indications

Smooth muscle spasms, including those accompanied by pain syndrome of varying intensity, and flatulence of various etiologies: bloating in functional gastrointestinal diseases, dyspepsia, aerophagia, Remkheld syndrome, postoperative period, gastritis, cardio and / or pylorospasm, enteritis, colitis, functional diarrhea, spastic colitis with constipation, irritable bowel syndrome, cholecystolithiasis, cholangiolithiasis, cholecystitis, pericholecystitis, cholangitis, papillitis; diseases of the urinary tract and gynecological diseases, accompanied by spasms of smooth muscles and flatulence.

As an adjunct before X-ray, ultrasound and instrumental examination of the abdominal and pelvic organs.

Application

The preparation is taken before meals, and, if necessary, when painful sensations appear, with a small amount of water. the duration of treatment is determined individually and depends on the presence and duration of the symptoms of the disease.

Children 6 to 12 years old: Take 1 capsule 3 times a day.

Adults and children over the age of 12: for functional gastrointestinal diseases, for diseases of the biliary tract, for diseases of the urinary tract and gynecological diseases - 2 capsules 3 times a day.

To prepare for X-ray and / or ultrasound examination, it is recommended to take 1 capsule 2 times a day and 1 capsule in the morning of the examination day the day before the examination.

The maximum daily dose is 6 capsules, which corresponds to 480 mg of phloroglucinol dihydrate and 750 mg of simethicone.

Contraindications

Hypersensitivity to phloroglucinol dihydrate, simethicone or other components of the preparation. intestinal obstruction, obstructive conditions of the gastrointestinal tract.

Side effects

In some cases, when using the preparation, allergic skin reactions (skin rashes, itching), bronchospasm may occur.

special instructions

Use during pregnancy and lactation. the preparation should not be administered in the i trimester of pregnancy. to use the preparation in the ii-iii trimester of pregnancy, you should consult your doctor.

For the period of breastfeeding, the use of the preparation should be discontinued.

Children. The preparation is used in children over the age of 6 years.

The ability to influence the reaction rate when driving or operating other mechanisms. Does not affect.

Interactions

It is necessary to avoid the interaction of fluroglucinol with strong analgesics, such as morphine or its derivatives, due to the possible spasmodic effect.

Overdose

To date, cases of overdose are unknown.

Storage conditions

At a temperature not higher than 25 ° C. do not freeze.