Glutargin Alkoclean 1g 10 tablets — Made in Ukraine — Free Delivery

Preparations used for liver diseases. Hepatotropic preparations. Arginine glutamate. A05B A01.

Glutargin is a salt of arginine and glutamic acid, which play an important role in providing biochemical processes of neutralization and excretion of a highly toxic metabolite of nitrogenous substances - ammonia from the body. The hypoammonaemic effects of the preparation are realized by activating the neutralization of ammonia in the ornithine cycle of urea synthesis, binding of ammonia to non-toxic glutamine, as well as enhancing the excretion of ammonia from the central nervous system and its excretion from the body. Thanks to these properties of Glutargin, the general toxic, including neurotoxic, effects of ammonia are reduced.

Glutargin also has a hepatoprotective effect due to antioxidant, antihypoxic and membrane stabilizing properties, and has a positive effect on the processes of energy supply in hepatocytes.

In case of alcohol intoxication, Glutargin stimulates the utilization of alcohol in the monooxygenase system of the liver, prevents the inhibition of the key enzyme of ethanol utilization - alcohol dehydrogenase; accelerates the inactivation and elimination of toxic products of ethanol metabolism as a result of an increase in the formation and oxidation of succinic acid; reduces the depressing effect of alcohol on the central nervous system due to the neurotransmitter properties of excitatory glutamic acid. Thanks to these properties, Glutargin exhibits antitoxic and sobering effects.

Glutargin does not have embryotoxic, gonadotoxic, mutagenic and teratogenic effects, does not cause allergic and immunotoxic reactions.

As part of the complex therapy of acute and chronic hepatitis of various etiologies, incl. in case of poisoning with hepatotropic poisons (pale toadstool, chemical and medicinal substances), with cirrhosis of the liver, leptospirosis. Hepatic encephalopathy accompanied by hyperammonemia.

Acute alcohol poisoning of mild and moderate severity, hangover syndrome, post-intoxication disorders caused by alcohol intake.

Relative contraindications are fever, hyperexcitability, severe violations of the filtration (nitrogen excretion) function of the kidneys.

Application during pregnancy or lactation. The safety of the clinical use of the preparation during pregnancy and lactation has not been studied.

The ability to influence the reaction rate when driving or operating other mechanisms. Does not affect.

Children. The efficacy and safety of using the preparation in childhood and adolescence have not been studied.

The preparation is prescribed for adults inside.

Hepatitis, hyperammonemia. Prescribe 3 tablets of 0.25 g (0.75 g) or 1 tablet of 0.75 g 3 times a day for 15 days, regardless of food intake. If necessary, the dose of the preparation and the course of treatment can be increased up to 20 days. The highest single dose is 2 g, the highest daily dose is 8 g.

Alcohol poisoning. Prescribe 4 tablets of 0.25 g (1 g) or 1 tablet of 1 g 4 times a day at intervals of 1-2.5 hours, in the next 2-3 days - 2 tablets of 0.25 g (0.5 g ) or ? tablets 1 g 3 times a day. In case of severe alcohol poisoning, after a course of treatment with Glutargin injections, Glutargin tablets are prescribed: 3 tablets of 0.25 g (0.75 g) or 1 tablet of 0.75 g 2 times a day, or 1? tablets 1 g 1 time per day for 20 days. For the prevention of alcohol intoxication - 2 g 60-120 minutes before drinking.

Symptoms: chest pain inherent to glutamic acid, atrioventricular block is possible.

Treatment: intravenous corticosteroids.

Rarely, there may be a feeling of mild discomfort in the gastrointestinal tract and nausea immediately after using the preparation, which go away on their own.

Interaction with other medicinal products and other types of interactions.

The effect of Glutargin on insulin secretion increases with the simultaneous use of aminophylline. Glutargin can enhance the effect of antiaggregatory agents (dipyridamole, etc.). Prevents and weakens neurotoxic phenomena that may occur with the use of isoniazid. Weakens the effect of vinblastine.

2 years.

Storage conditions.