Herpevir aciclovir ointment 2.5% (acyclovir), 5g— Made in Ukraine — Free Delivery

Pharmacodynamics. acyclovir is an antiviral preparation with high in vitro activity against herpes simplex virus types I and II. the toxic effect on the cells of the host organism is minimal. getting into cells infected with the herpes virus, acyclovir is phosphorylated to form an active compound - acyclovir triphosphate. the first step in this process depends on the presence of virus-coded thymidine kinase. Acyclovir triphosphate acts as an inhibitor and substrate for viral DNA polymerase, preventing further viral DNA synthesis without affecting normal cellular processes.

Pharmacokinetics. The level of systemic absorption of acyclovir after repeated topical application of Gerpevir ointment is minimal.

Infections of the lips and face caused by the herpes simplex virus herpes labialis.

The preparation is intended for external use only.

For children over the age of 12 and adults, Gerpevir ointment is applied 5 times a day at approximately 4-hour intervals, except at night. It is important to start treatment as soon as possible at the onset of the infection, preferably during the prodromal period or at the erythema stage. You can start treatment in the later stages - papules or bladder.

Treatment should be continued for at least 4 days. If healing does not occur, treatment can be continued for up to 10 days. If the symptoms of the disease do not disappear after 10 days of treatment, you should consult a doctor. Hands should be washed before and after applying the ointment and avoid excessive rubbing or touching the affected area with a towel to prevent exacerbation or transmission of infection.

Hypersensitivity to acyclovir, valacyclovir, propylene glycol or other components of the ointment.

In some patients, when using the ointment, a temporary, rapidly passing sharp or burning pain may appear. in about 5% of patients, slight drying and flaking of the skin is possible. also, in a small proportion of patients, erythema (redness) and itching are possible. very rarely, cases of contact dermatitis have been reported after topical application of acyclovir preparations, and most often this is due to the components of the ointment base, and not to acyclovir. there are isolated reports of immediate hypersensitivity reactions, including angioedema, due to topical application of acyclovir.

The ointment should only be used to treat cold sores on the lips and face. it is not recommended to apply the ointment to the mucous membranes of the mouth, eyes and use it to treat genital herpes. accidental contact with the eyes should be avoided.

Individuals who suffer from particularly severe and repetitive manifestations of Herpes labialis need the advice of a doctor. Patients with herpes lips should be warned against contact transmission of the virus to others, especially if there are open lesions (for example, washing hands before and after using the ointment). Not recommended for use in immunocompromised patients. Such individuals need medical advice regarding the treatment of any infection.

During pregnancy and lactation, the preparation is recommended to be used only in cases where the benefit, according to the doctor, outweighs the risk.

Children. There is insufficient data on the safety of using the preparation in children under the age of 12, therefore it is recommended to use the preparation in children over the age of 12.

The ability to influence the reaction rate when driving and working with other mechanisms. No data.

No interactions have been identified.

Due to minimal systemic exposure, adverse effects are unlikely if the entire tube of ointment is accidentally applied orally or topically. if an overdose is suspected, seek medical attention.

In its original packaging at a temperature not exceeding 25 ° C.