LIOTON 1000 GEL 100G — MADE IN GERMANY — FREE SHIPPING
Lioton gel is a preparation in the form of a gel, which is indicated for use as an adjuvant in the treatment of phlebitis, thrombophlebitis and varicose veins of the lower extremities. It can also be used for swelling, contusions and subcutaneous hematomas.
1g of gel contains: active substance: 8.5 mg (1000IU) of sodium heparin and auxiliary substances: carbomer 940, propyl parahydroxybenzoate, methyl parahydroxybenzoate, ethanol 96%, lavender oil, orange oil, triethanolamine, purified water.
anticoagulant, anti-edema and anti-inflammatory.
the preparation should be used 1-3 times a day, by applying the gel to the affected area of the skin.
Contraindications: allergy to any component of the preparation, as well as: open wounds on the skin, bleeding. The gel should not be applied around the eyes, mouth and nose.
Before use, read the leaflet, which contains indications, contraindications, data on side effects, dosage and information on the use of the medicinal product, or consult your doctor or pharmacist, as each preparation used improperly is a threat to your life or health.
Instruction for use Lioton 1000 gel.
Indications: Lioton 1000 in the form of a gel is a drug indicated for use on the skin. It contains heparin, thanks to which it has local anticoagulant, anti-edema and anti-inflammatory properties. Intended for the supportive treatment of superficial vein diseases such as phlebitis, thrombophlebitis, varicose veins of the lower extremities; in subcutaneous hematomas, bruises and edema. Immediately after application, the gel is easily absorbed through the skin, alleviating the symptoms of superficial vein insufficiency and giving a pleasant feeling of cooling.
Properties: Lioton 1000 is characterized by the content of a high concentration of heparin in a unique gel formula that effectively penetrates the skin. Heparin has anticoagulant and anti-inflammatory properties. It promotes the improvement of microcirculation and acts against swelling. Its unique combination with the Lioton® 1000 gel formula allows you to effectively combat swelling and pain caused by the feeling of tension. The use of Lioton® 1000 gel is associated with a very low risk of side effects, and it is also characterized by attractive cosmetic features. The gel is perfectly absorbed, has a pleasant lavender scent and provides a quick cooling effect. The product does not stain and is convenient for everyday use - both at home and at work. If you want to feel a quick relief - reach for Lioton 1000 gel.
Composition: Active substance: sodium heparin (Heparinum natricum).
1 g of gel contains 8.5 mg (1000 IU) of sodium heparin.
Other ingredients: carbomer 940, propyl parahydroxybenzoate, methyl parahydroxybenzoate, ethanol 96%, lavender oil, orange oil, triethanolamine, purified water.
Use: Lioton 1000 gel is intended for use on the skin.
Apply the drug 1 to 3 times a day, applying 3-10 cm of gel to the skin surface and gently massaging until the gel is absorbed.
In the case of acute swelling after blunt injuries, use the drug for up to 10 days, and for the treatment of superficial vein diseases - 1 to 2 weeks.
Important information: Lioton 1000 is not recommended in case of known hypersensitivity to heparin or any of the other ingredients of the drug.
It should not be used on open wounds or oozing skin lesions. Not recommended for use around the eyes, nose and mouth. Lioton 1000 is not recommended in the presence of bleeding. The drug must not be administered orally.
Package: 100 gr.
Before use, read the leaflet, which contains indications, contraindications, data on side effects and dosage as well as information on the use of the medicinal product, or consult your doctor or pharmacist, as each drug used improperly is a threat to your life or health.
3. How to use Lyoton® 1000 IU/g gel
If you experience any side effects, contact your doctor or pharmacist. This applies to any possible side effects,
including those not described in this leaflet. See section 4.
6. Contents of the package and other information
ÿ elimination of edema and bruising in the area of joints and muscles after their injuries and
Lyoton® 1000 IU/g gel can be used as a single preparation -
see a doctor.
Package leaflet: Information for the patient
The active ingredient of Lyoton® 1000 IU/g gel is heparin (heparin sodium salt). The drug Lyoton is
available in the form of a gel intended for application to the skin. When applied to affected areas, heparin
prevents the formation of blood clots in superficial veins, improves local microcirculation (blood circulation in
small vessels) and reduces
2. What you need to know before you use Lyoton® 1000 IU/g gel
ÿ symptomatic treatment for diseases of the superficial veins (such as
Read the entire package leaflet carefully before you start using this drug because it contains important
information for you.
4. Possible side effects
Keep this leaflet. You may need to read it again.
If after 7 days the symptoms worsen or there is no improvement,
ÿ reduce the severity of phenomena that occur after surgical interventions performed on the veins (for
example, bruising and swelling);
If you need more information or advice, ask a pharmacist.
Lyoton® 1000 IU/g gel
Contents of this leaflet
5. How to store Lyoton® 1000 IU/g gel
if there are indications for local treatment - or in combination with systemic
1 What Lyoton® 1000 IU/g gel is and what it is used for
Heparin sodium salt
1. What Lyoton® 1000 IU/g gel is and what it is used for
Lyoton® 1000 IU/g gel is used for:
for example, diseases that are characterized by varicose veins and their
complications, the formation of blood clots in the affected veins with or without
inflammation of the vein wall, inflammation of the tissues surrounding the veins, as
well as ulcers that appear on the skin in the area of varicose veins); ÿ treatment for
inflammation of the vein wall affected due to surgical
This medicine should be used exactly as directed in this package insert, or as directed by your doctor
Other medicines and Lyoton® 1000 IU/g gel
lactation is absent.
bleeding on the skin or there is a skin infection: Lyoton® 1000 IU / g gel should not be applied to such
places. Lyoton® 1000 IU/g gel should also not be used on areas not covered by the skin (eg, genitals,
If you are pregnant or breastfeeding, or if you are pregnant or planning to become pregnant, ask your doctor or
pharmacist for advice before using this medicine.
Lyoton® 1000 IU/g gel contains methyl parahydroxybenzoate
Influence on the ability to drive vehicles and maintain mechanisms
2 What you need to know before you use Lyoton® 1000 IU/g gel
Children and teenagers
ÿ If you have an increased tendency to bleed. In this case, your doctor should carefully consider the
possibility of using Lyoton® 1000 IU/g gel;
Pregnancy, breastfeeding and childbearing
ÿ If you develop signs of allergy (hypersensitivity) after using Lyoton® 1000 IU/g gel. In this case, the use of
Lyoton® 1000 IU/g gel should be discontinued immediately;
ÿ If you have open wounds in the area where the drug is to be applied,
Data on the use of the drug Lyoton® 1000 gel during pregnancy or
Warnings and Precautions
Tell your doctor or pharmacist if you are currently taking, have recently taken or may have taken any other
(E218), propyl parahydroxybenzoate (E216), neroli flavoring and lavender oil.
Take special care if you are taking oral anticoagulants (i.e. medicines to prevent blood clots). In these cases,
application of heparin to the skin may prolong the clotting time.
Before you start using Lyoton® 1000 IU/g gel, ask your doctor or pharmacist for advice:
This medicinal product contains excipients methyl parahydroxybenzoate (E218), propyl
parahydroxybenzoate (E216) as
Lyoton® 1000 IU/g gel must not be used
- if you are allergic to heparin sodium or any of the other ingredients of this medicine (listed in section 6).
Lyoton® 1000 IU/g gel should not be used in children and adolescents because the
safety and efficacy of the drug in this age group has not been established.
Lyoton® 1000 IU/g gel does not affect the ability to drive and operate machinery.
If you forget to apply Lyoton® 1000 IU/g gel
Allergic reactions to heparin after its application to the skin are very rare (less than 1 in
10,000 patients). In isolated cases (frequency unknown: according to the available data,
the frequency cannot be estimated) hypersensitivity reactions may develop, such as
reddening of the skin and itching. These reactions usually disappear soon after the drug is
There have been no reports of overdose of Lyoton® 1000 IU/g gel.
preservatives. They can cause allergic reactions, possibly delayed
Reporting side effects
If you experience any side effects, contact your doctor or pharmacist. This applies to any possible side
effects, including those not described in this leaflet. You can also report side effects directly through the
national alert system.
In case of overdose, it is possible to neutralize the action of heparin protamine
Apply the gel to the affected area one to three times a day and rub in with massage movements. It is
recommended to squeeze out a strip of gel 3-10 centimeters long from the tube. If your symptoms get worse or if
there is no improvement after 7 days, contact your doctor.
4 Possible side effects
If you have applied more Lyoton® 1000 IU/g gel than
Like all medicines, this medicine can cause side effects, although not everybody gets them.
This medicine should be used strictly as directed by your doctor or pharmacist. If you have any doubts,
ask your doctor or pharmacist.
If you forget to apply Lyoton® 1000 IU/g gel, apply it as soon as you remember. Do not use a double dose to
make up for a missed application.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
Dosage and method of application
This medicine contains flavors that include citral, citronellol, coumarin, D-limonene, farnesol, geraniol, and linalool.
Citral, citronellol, coumarin, D-limonene, farnesol, geraniol and linalool may cause allergic reactions.
3 How to use Lyoton® 1000 IU/g gel
By reporting side effects, you can help gather more information about the safety of this drug.
Lyoton® 1000 IU/g gel is a gel for application to the surface of the skin.
(international units) per 1 g of gel.
5 How to store Lyoton® 1000 IU/g gel
A. Menarini Manufacturing Logistics and Services s.r.l., Via Sette Santi 3, 50131 Florence,
Glieniker Veg 125
Keep out of the reach of children.
Other ingredients: ethanol 96%, carbomer, trolamine, methyl parahydroxybenzoate, propyl
parahydroxybenzoate, neroli flavor (which contains linalool, D-limonene, geraniol, citral,
citronellol and farnesol), lavandin oil (which contains linalool, D-limonene, geraniol and
coumarin), purified water.
6 Contents of the package and other information
Registration certificate holder
What is in Lyoton® 1000 IU/g gel
The active substance is heparin sodium salt: 1000 IU
A. Menarini Industry Pharmaceutical Riunite s.r.l. (Menarini Group), Via Sette Santi 3,
50131 Florence, Italy
After the first opening of the package, Lioton® 1000 IU/g gel can be used within
Lioton® 1000 IU/g gel is a viscous gel, colorless or slightly yellowish, almost transparent,
with an aromatic odor.
12489 Berlin, Germany
The drug is available in tubes containing 30 g, 50 g and 100 g of gel. Not all package sizes
may be available for sale.
Do not dispose of any medication down the drain. Talk to your pharmacist
about how to dispose of an unused drug. These measures contribute to the protection
of the environment.
Date of last revision of this leaflet: 06/2021
Store below 25°C.
What Lyoton® 1000 IU/g gel looks like and contents of the pack
After the expiration date indicated on the carton and tube, do not use this medicine
again. The expiration date is the last day of the specified month.
Berlin-Chemie AG (MENARINI GROUP)
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