Nazol Kids nasal drops 0.25% 10 ml — Made in Germany — Free Delivery
(Nazol Kids )
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Description Nazol Kids nasal drops 0.25% 10 ml — Made in Germany — Free Delivery
Pharmacological properties
Pharmacodynamics. Phenylephrine hydrochloride is a synthetic adrenergic agonist. stimulating α-adrenergic receptors of blood vessels, it has a pronounced vasoconstrictor effect. the vasoconstrictor effect is manifested by a decrease in blood flow and edema of the nasal mucosa, paranasal sinuses and the Eustachian tube. thereby restoring nasal breathing, disturbed by flu, colds and allergic diseases.
Pharmacokinetics. Local vasoconstriction of the nasal mucosa and paranasal sinuses occurs 3-5 minutes after the preparation is injected into the nasal cavity. The decongestant effect lasts up to 6 hours.
Indications
Acute rhinitis due to colds, flu, allergic diseases, sinusitis. acute otitis media (as an adjuvant).
Application
Children aged 2-6 years - 1-2 doses of spray in each nasal passage, no more than 6 hours later; children aged 6–12 years - 2-3 doses of spray in each nasal passage, no more than 4 hours later. The bottle should be kept upright. the duration of the course of treatment usually does not exceed 3 days.
Contraindications
Hypersensitivity to the components of the preparation (allergic reactions), severe forms of ag, tachysystolic heart rhythm disturbances, acute cardiovascular diseases, decompensated heart failure, cardiac conduction disturbances, renal failure, thyrotoxicosis, acute pancreatitis, hepatitis, inflammation of the skin and mucous membrane of the anterior region nasal cavity and a tendency to form nasal crusts (atrophic rhinitis), conditions after transsphenoidal hypophysectomy, simultaneous use with MAO inhibitors and within 15 days after stopping treatment with MAO inhibitors.
Side effects
In isolated cases, such side effects are possible.
At the site of application: irritation at the site of application, sneezing, burning, tingling in the nose.
From the side of the cardiovascular system: flushing of the face, heart rhythm disturbances, bradycardia, increased blood pressure.
From the nervous system: dizziness, fear, headache.
On the part of the immune system: allergic reactions, including cross-reactions in the presence of allergies to other sympathomimetics, which may manifest as rash, itching, urticaria, angioedema (hands, face or throat), a feeling of heaviness in the chest, shortness of breath.
When using the preparation in doses exceeding the recommended ones, the manifestations indicated in the OVERDOSE section are possible.
Special instructions
To avoid the spread of infection, individual use of the nebulizer is recommended.
The persistence of swelling of the nasal passages after 3 days of use may indicate the presence of curvature of the nasal septum, purulent sinusitis, adenoids, allergic rhinitis, persistent bacterial infection or other diseases requiring the consultation of a specialized specialist and specialized complex therapy.
This preparation should be used with caution in patients with hypertension, cardiovascular diseases, thyroid diseases (except for those specified in CONTRAINDICATIONS), angle-closure glaucoma, diabetes mellitus.
In these cases, you should consult your doctor before using the preparation.
Use during pregnancy and lactation. The preparation is not intended for use during pregnancy and lactation.
Children aged 2–12 years. The preparation should be used under adult supervision.
If children under the age of 12 develop nervousness, dizziness or insomnia, discontinue use and consult a doctor.
The ability to influence the reaction rate when driving or working with other mechanisms. This medicinal product is not expected to affect the reaction rate when driving or operating other machinery.
Interactions
It should not be used in conjunction with other vasoconstrictor preparations (for any route of administration of the latter), as well as with antihypertensive preparations (β-adrenergic receptor blockers).
Atropine sulfate blocks phenylephrine-induced reflex bradycardia and increases the vasopressor response to phenylephrine. Simultaneous administration of phenylephrine with β-adrenergic receptor blockers can lead to hypertension and excessive bradycardia with possible heart block. It should be used with caution with thyroid hormones, preparations that affect cardiac conduction (cardiac glycosides, antiarrhythmic preparations). When combined with preparations that predetermine the excretion of potassium, for example with some diuretics such as furosemide, hypokalemia may increase and arterial sensitivity to vasopressor preparations such as phenylephrine may decrease.
The simultaneous administration of phenylephrine and other sympathomimetics can lead to additional stimulation of the central nervous system to an extremely high level, which is accompanied by nervousness, irritability, and insomnia.
Seizures are also likely. In addition, the simultaneous use of other sympathomimetics together with phenylephrine can lead to an increase in the severity of the vasoconstrictor effect or cardiovascular effect of either of these two medications.
Concomitant use with MAO inhibitors is contraindicated. You should start using this preparation at least 15 days after stopping therapy with MAO inhibitors, since pressor effects may increase (see CONTRAINDICATIONS).
The simultaneous use of phenylephrine with linezolid is not recommended.
Overdose
Although with local application, side systemic reactions usually do not occur, however, in case of an overdose, an increase in the manifestations of side reactions is possible, especially with prolonged use. cardiac arrhythmias, increased blood pressure, arterial hypotension, pain and discomfort in the region of the heart, palpitations, shortness of breath, noncardiogenic pulmonary edema, agitation, convulsions, headache, tremors, sleep disturbances, anxiety, anxiety, nervousness, irritability, inappropriate behavior may develop , psychosis with hallucinations, insomnia, weakness, anorexia, nausea, vomiting, oliguria, urinary retention, painful or difficult urination, facial flushing, feeling of coldness in the extremities, paresthesias, skin pallor, piloerection, increased sweating, hyperglycemia, vascularity, hypokalemia and vessels of internal organs, a decrease in blood flow to vital organs, which can lead to a deterioration in the blood supply to the kidneys, metabolic acidosis, an increase in the load on the heart due to an increase in the general resistance of peripheral vessels. severe consequences of vasoconstriction can occur more often in patients with hypovolemia and severe bradycardia. there is no specific antidote for phenylephrine poisoning. symptomatic treatment.
Storage conditions
At a temperature not higher than 25 ° C.
Tags: Nazol
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