Nitroxoline 50 mg, 50 tablets — Made in Ukraine — Free Delivery

Product description

Nitroxoline tablets are used for the following indications:

• acute, chronic and recurrent urinary tract infections caused by gram-positive and gram-negative microorganisms and fungi sensitive to nitroxoline;
• prevention of recurrent urinary tract infections.

Before prescribing the preparation, it is necessary to conduct a microbiological study to identify the infectious agent and check its sensitivity to nitroxoline. However, if there is reason to believe that the infection is most likely caused by microorganisms that are susceptible to nitroxoline, treatment can be started pending test results.

Compound

The active ingredient is nitroxoline (one tablet contains nitroxoline (in terms of 100% dry matter) - 50 mg).

Excipients: potato starch, lactose monohydrate, calcium stearate, colloidal anhydrous silicon dioxide, talc; film coating 85F35260 Opadry II Red: partially hydrolyzed polyvinyl alcohol, macrogol, talc, titanium dioxide (E 171), special red AG (E 129), sunset yellow FCF (E 110).

Contraindications

• hypersensitivity to nitroxoline or to any other component of the preparation, as well as to other quinolones;
• severe hepatic and renal failure (creatinine clearance less than 0.33 ml / s).

Mode of application

Adults: The average recommended daily dose is 400 mg (two tablets 4 times daily before meals). In severe diseases, the daily dose can be increased to 800 mg (4 tablets 4 times a day). The maximum daily dose for adults is 800 mg.

Children aged 3 to 5 years: the recommended daily dose is 200 mg (one tablet 4 times a day).

Children from 5 years old: the recommended daily dose is 200-400 mg (1-2 tablets 4 times a day).

The duration of the course of treatment is 2-3 weeks.

Patients can take the preparation continuously for one month. In chronic infections, the preparation should be prescribed by repeated courses of two weeks duration with weekly breaks (the course of treatment can last several months).

Application features

Pregnant

The safety and efficacy of the preparation during pregnancy and lactation have not been established, therefore, nitroxoline should not be prescribed during these periods.

Children

Children under 3 years of age should not use the preparation in the form of film-coated tablets.

Drivers

There is no evidence that the preparation can adversely affect the reaction rate in drivers and people who work with equipment.

Overdose

There were no reports of overdose cases. If the dose is exceeded, symptomatic therapy is performed.

Side effects

Allergic reactions: skin rash, itching, which quickly disappear after stopping the preparation; allergic reactions with the development of thrombocytopenia.

Digestive system: possible dyspeptic symptoms (nausea, vomiting, loss of appetite), which can be prevented by using the preparation with meals.

Nervous system: headache, ataxia, paresthesia, polyneuropathy.

Hepatobiliary system: decreased activity of transaminases, impaired liver function.

Urinary system: a decrease in the content of uric acid in the blood plasma.

Storage conditions

Store in its original packaging at a temperature not exceeding 25 ° C, out of the reach of children.

Shelf life is 4 years.