Pulmolor powder for oral suspension 60 ml — Made in India — Free Delivery

(Pulmolor)
Pulmolor powder for oral suspension 60 ml — Made in India  — Free Delivery
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Sava Healthcare Limited Brand: Sava Healthcare Limited
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Description Pulmolor powder for oral suspension 60 ml — Made in India — Free Delivery

Pharmacological properties

Pulmolor has a pronounced expectorant effect, softens and soothes dry cough, facilitates breathing, normalizes the secretion of bronchial mucus, improves sputum discharge, and reduces inflammation of the respiratory tract. has an anti-exudative effect, reduces spasm of smooth muscles of the bronchi and edema of tissues, including the mucous membranes of the nose, throat, maxillary sinuses and respiratory tract, reduces capillary permeability, reduces nasal congestion, lacrimation, sneezing, itching of the palate and nose, redness of the eyes.
Ambroxol hydrochloride is a secretolytic and secretomotor agent. It has a pronounced expectorant and a slight antitussive effect. It stimulates serous cells of the glands of the bronchial mucosa, increases the amount of mucous secretion and thus normalizes the ratio of serous and mucous components. This helps to normalize the rheological parameters of sputum, reduce its viscosity and adhesive properties. Directly stimulates the mobile activity of the ciliated epithelium of the bronchi, prevents its adhesion and improves mucociliary evacuation of sputum. Ambroxol increases the content of surfactant in the lungs, and also prevents its destruction in pneumocytes. As a mucolytic agent and as an expectorant, Ambroxol improves the function of external respiration. The preparation reduces the hyperreactivity of bronchial muscles in BA. Ambroxol exhibits anti-inflammatory effect, antioxidant properties, stimulates local immunity and renewal of the natural surfactant layer. When taking ambroxol, patients' complaints of cough and phlegm are significantly reduced according to the intensity of treatment. Ambroxol hydrochloride increases the concentration of antibiotics in the lungs and thus improves the course of respiratory diseases in bacterial infections of the lungs.
Loratadine is a selective blocker of peripheral H1-histamine receptors with prolonged action. Has no central sedative effect. It has anti-allergic properties, weakens the spasm of the smooth muscles of the bronchi, reduces the sensitivity of the bronchi to histamine, eliminates dry cough of allergic etiology, reduces capillary permeability, reduces tissue edema, rhinorrhea, lacrimation, sneezing, itching of the palate and nose, redness of the eyes. Prevents the development and facilitates the course of allergic reactions. Its action is carried out by competitive blocking of H1-histamine receptors on effector cells due to inhibition of calcium flow into cells, inhibition of histamine release (membrane stabilizing function), inhibition of eosinophil chemotaxis and their accumulation in the mucous membrane. The antihistamine effect of loratadine manifests itself within 1-3 hours after administration, reaches a maximum after 8-12 hours and lasts 24 hours. After 28 days of application of loratadine, addiction is not observed.

Indications

Symptomatic therapy of acute and chronic diseases of the respiratory tract with a spastic and allergic component associated with impaired bronchial secretion and weakening of mucus movement. prescribed for acute and chronic bronchitis, hoble, pneumonia, in conditions that are accompanied by bronchial hyperreactivity.
In ENT practice, in order to dilute the secretion and reduce edema, it is prescribed for rhinitis, including allergic, in the complex treatment of sinusitis and otitis media.

Application

Pills. used in adults and children over the age of 12 years by mouth, 1 tablet 2 times a day.
The tablets should be taken after meals and washed down with water. The duration of treatment is up to 14 days.
Powder for suspension preparation. Children aged 6-12 years: 2.5 ml each
2-3 times a day.
Adults and children over the age of 12 years: 5 ml 2 times a day.
Suspension preparation. To prepare the suspension, boiled chilled water is added to the bottle to the mark, then shaken. It is taken after meals. Shake well before each use.
The duration of treatment is up to 14 days. You should consult your doctor if symptoms persist and / or worsen after 14 days.

Contraindications

Hypersensitivity to any component of the preparation.

Side effects

The preparation is usually well tolerated.
On the part of the skin: alopecia.
From the immune system: hypersensitivity reactions, including rash, urticaria, itching, anaphylactic reactions (including anaphylactic shock), angioedema, shortness of breath (as a symptom of a hypersensitivity reaction), erythema; severe skin lesions: Stevens-Johnson syndrome and toxic epidermal necrolysis (Lyell's syndrome).
Since the tablets contain methylparaben and propylparaben, allergic reactions (probably delayed) and bronchospasm are possible.
Due to the sodium metabisulfite content in powder for oral suspension - the development of hypersensitivity reactions and bronchospasm.
From the nervous system: dysgeusia (taste disorder), dizziness, convulsions, headache, nervousness, fatigue, drowsiness, insomnia.
From the digestive tract: nausea, decreased sensitivity in the oral cavity, vomiting, diarrhea, dyspepsia, abdominal pain, dry mouth and throat, constipation, salivation, gastritis.
From the respiratory system: rhinorrhea.
From the hepatobiliary system: abnormal liver function.
From the side of the cardiovascular system: tachycardia, palpitation.
From the urinary system: dysuria.
General disorders: fever, reactions from the mucous membranes, increased appetite.

Special instructions

Before performing skin tests for reactivity, you should stop taking the preparation for 48 hours.
The preparation contains lactose, therefore, patients with rare hereditary galactose intolerance, Lapp lactase deficiency or malabsorption of glucose and galactose should not take this preparation.
Only a few reports have been received of severe skin lesions: Stevens-Johnson syndrome and toxic epidermal necrolysis (Lyell's syndrome) associated with the use of expectorants such as ambroxol hydrochloride. For the most part, they could be explained by the severity of the underlying disease in patients and the simultaneous use of another preparation. Also in the early stages of Stevens-Johnson syndrome or Lyell's syndrome, patients may have non-specific, flu-like symptoms such as fever, aches, rhinitis, cough, and sore throat. Mistakenly, with such nonspecific, like signs of the onset of influenza symptoms, you can apply symptomatic treatment with preparations for cough and cold. Therefore, if new lesions of the skin or mucous membranes appear, you should immediately seek medical attention and stop treatment with Ambroxol hydrochloride.
Since ambroxol can increase mucus secretion, the preparation should be used with caution in case of impaired bronchial motility and increased mucus secretion (for example, in such a rare disease as primary ciliary dyskinesia).
Patients with impaired renal or liver function (for example, jaundice, hepatitis, hepatonecrosis) should take the preparation only after consulting a doctor; the preparation should be used with caution (namely, the interval between use should be increased or the dose should be reduced). In patients with severe renal impairment, an accumulation of metabolites that are formed in the liver is expected.
5 ml of the finished suspension contains 0.75 g of sucrose, which should be taken into account in the total amount of sucrose consumed per day for patients with diabetes mellitus and on a diet low in sugar.
Use during pregnancy and lactation. Since the experience of using the preparation in pregnant women is insufficient, it is not recommended to take it during pregnancy. Since the preparation passes into breast milk, it is not recommended to use it during breastfeeding.
Children. Do not administer tablets to children under 12 years of age.
Suspension powder should not be administered to children under 6 years of age.
The ability to influence the reaction rate when driving or working with other mechanisms. In general, the preparation does not affect the rate of reactions when driving or operating other mechanisms. The patient must be informed that cases of drowsiness are very rarely possible, which can affect the ability to drive vehicles or work with other mechanisms.

Interactions

The simultaneous administration of Pulmolor with antibiotics has an advantage over the appointment of only an antibiotic. pulmolor increases the concentration of antibiotics in the lungs and, thus, improves the course of respiratory diseases in case of bacterial infections of the lungs.
The preparation does not potentiate the effects of alcohol.
Do not take at the same time with cough medicines that make it difficult to remove phlegm.
A potential interaction is possible with all known inhibitors of CYP 3A4 or CYP 2D6, which leads to an increase in loratadine levels, and this, in turn, may cause an increase in the incidence of adverse reactions.
In controlled studies, an increase in the concentration of loratadine in blood plasma was reported after simultaneous use with ketoconazole, erythromycin and cimetidine, which was not accompanied by clinically significant changes (including on the ECG).
Other preparations that suppress liver function should be used with caution when used concomitantly.

Overdose

Drowsiness, tachycardia, headache, nausea, vomiting, diarrhea, decreased blood pressure.
Treatment. In case of overdose, symptomatic and supportive treatment is recommended. Standard measures are taken to eliminate the preparation that has not been absorbed in the stomach: gastric lavage, the use of crushed activated carbon with water.
Loratadine is not excreted by hemodialysis. It is also unknown whether it is cleared by peritoneal dialysis. After emergency care, the patient should remain under medical supervision.

Storage conditions

Suspension - in its original packaging at a temperature not exceeding 25 ° C. after preparation, the suspension is stored for 14 days at a temperature of 2–8 ° C.
Tablets - in their original packaging at a temperature not exceeding 25 ° C.
Keep out of the reach of children.

Tags: Pulmobreathe

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