Sedavit 20 tablets — Made in Ukraine — Free Delivery

Pharmacological properties

Complex extract for sedavit is obtained from rhizomes with valerian roots, hawthorn fruits, St. John's wort, peppermint leaves, hop cones. the pharmacological action of the preparation is due to the properties of the components that make up its composition. biologically active substances of extracts of medicinal plants have a positive effect on the functioning of the nervous and cardiovascular systems and have a predominantly sedative, anxiolytic effect, eliminate the feeling of fear, mental stress. vitamins are components of enzyme systems involved in the redox processes of the body. pyridoxine hydrochloride (vitamin b6) - normalizes the functioning of the central and peripheral nervous system; nicotinamide (vitamin pp) - participates in the processes of tissue respiration, fat and carbohydrate metabolism.

The pharmacological efficacy of the preparation depends on the combined action of its components, therefore, kinetic studies are impossible, since all the components together cannot be determined using markers or biological studies.

Indications

"Manager" syndrome (a state of constant mental stress); neurasthenia and neurasthenic reactions, accompanied by irritability, anxiety, fear, fatigue, distraction, memory impairment, mental exhaustion; neurocirculatory dystonia of the hypertensive and cardiac type; asthenic syndrome (hypersthenic form); stage i; insomnia (mild forms); itchy dermatoses (eczema, urticaria); headache due to nervous tension; migraine; as a symptomatic agent for climacteric syndrome and mild forms of dysmenorrhea; as well as to eliminate the symptoms that occur in diseases of the thyroid gland and diabetes mellitus (except for decompensated diabetes mellitus).

Application

Sedavit pills. for adults and children aged 12 years and older, the preparation is prescribed 2 tablets 3 times a day. the tablets are swallowed without chewing, with a small amount of liquid. in case of nausea, the preparation should be taken with meals. if necessary, a single dose is increased to 3 tablets. in case of undesirable reactions from the nervous system (drowsiness, dizziness), 1 tablet is prescribed 3 times a day. the interval between doses is 8 hours. The preparation can be used once in a dose of 2-3 tablets 30-60 minutes before the expected psychoemotional load.

The course of treatment depends on the form and severity of the disease, the nature of concomitant therapy, the achieved treatment effect and is determined by the doctor.

Sedavit oral solution. For adults and children over the age of 12, the preparation is prescribed orally 3 times a day, 5 ml. If necessary, a single dose is increased to 10 ml. In the event of undesirable reactions from the nervous system (drowsiness, lethargy), 2.5 ml are prescribed in the morning and afternoon and 5 ml at night. The interval between doses is 8 hours. The preparation can be used once in a dose of 5-10 ml 20-30 minutes before a possible emotional stress. The preparation is taken undiluted or together with drinks (tea, juice). In case of nausea, the preparation is taken with meals.

Contraindications

Hypersensitivity to the components of the preparation, depression and conditions accompanied by inhibition of the central nervous system, BA, spasmophilia, severe arterial hypotension, bradycardia, myasthenia gravis, gastric ulcer and duodenal ulcer, ischemic heart disease, liver disease, hyperuricemia, gout, decompensated diabetes mellitus, urine ...

Side effects

In isolated cases, the following undesirable effects may appear.

Allergic reactions, including flushing, rash, itching, edema, urticaria, anaphylactic reactions, including anaphylactic shock.

From the side of the central and peripheral nervous system: drowsiness, fatigue, dizziness, depressed emotional state, agitation, headache, paresthesia, weakness, decreased performance.

From the digestive tract: nausea, pain and abdominal cramps, vomiting, heartburn, increased gastric secretion, intestinal dysfunction (diarrhea, constipation).

From the side of the cardiovascular system: bradycardia, lowering blood pressure, tachycardia, arrhythmia.

On the part of the skin: photosensitivity in sensitive persons, dermatitis, dry skin.

On the part of the musculoskeletal system: numbness of the limbs, muscle weakness.

From the side of metabolism: with prolonged use in high doses - a decrease in glucose tolerance.

Deviations of biochemical parameters from the norm: increased levels of AST, LDH, ALP, blood glucose, hyperuricemia.

Special instructions

The preparation contains lactose (tablets) and sorbitol (solution). patients with rare hereditary disorders of carbohydrate metabolism, in particular, intolerance to galactose, fructose, lactase deficiency of papa or glucose-galactose malabsorption syndrome, should not take this preparation.

When using the preparation, patients, especially those with fair skin, should avoid prolonged exposure to ultraviolet radiation (sunbathing, tanning beds, diathermy).

In patients with gastroesophageal reflux (heartburn), heartburn may increase.

The preparationshould be used with caution in patients with changes in blood pressure and diabetes mellitus. It is necessary to monitor blood pressure and blood glucose levels.

Do not take with alcohol.

Use during pregnancy and lactation. It is not recommended to prescribe the preparation during pregnancy and lactation.

The ability to influence the reaction rate when driving or working with other mechanisms. When using the preparation, you should refrain from driving vehicles and working with potentially dangerous mechanisms.

Children. The safety and efficacy of the preparation for children under 12 years of age have not been established; therefore, the preparation should not be used in children under 12 years of age.

Interactions

The preparation  enhances the effect of substances that have a sedative effect on the central nervous system, as well as alcohol. a mutual decrease in the severity of the action of levodopa and pyridoxine hydrochloride is possible.

Concomitant use of cycloserine, hydralazine, isoniazid, penicillamine and oral contraceptives causes an increased need for pyridoxine.

St. John's wort can cause induction of isoenzymes 3A4, 1A2 and 2C9 of cytochrome P450, which can lead to a decrease in the severity of the action of other preparations taken simultaneously and metabolized by these isoenzymes. In this regard, the simultaneous use of the preparation with:

indinavir or other antiretroviral preparations;

cyclosporine, digoxin, theophylline, irinotecan, tacrolimus, hypolipidemic agents (simvastatin, etc.), fexofenadine, tricyclic antidepressants (amitriptyline, nortriptyline), antiepileptic preparations (carbamazepine, serum phenytobarbital) sertraline, paroxetine), buspirone, as well as triptans (sumatriptan, naratriptan, zolmitriptan) and antihypertensive preparations - calcium channel blockers;

warfarin and other anticoagulants - coumarin derivatives;

oral contraceptives (due to a decrease in the effectiveness of contraceptives with the occurrence of irregular bleeding, the onset of unwanted pregnancy is not excluded).

It is not recommended to use the preparation with cardiac glycosides.

Diuretics - when combined with pyridoxine, the effect of diuretics is enhanced.

Hypnotics and sedatives - when used in combination

Antiparkinsonian preparations - when combined with pyridoxine, the effectiveness of preparations for the treatment of Parkinson's disease decreases.

Corticosteroids - when combined with pyridoxine, the amount of vitamin B6 in the body decreases.

With the simultaneous use of nicotinic acid with antithrombotic agents or acetylsalicylic acid, there may be a risk of bleeding.

The use with antihypertensive preparations leads to an increase in arterial hypotension, with antidiabetic preparations - a decrease in the severity of the hypoglycemic effect of the latter. Use with other lipid-lowering preparations increases the risk of developing toxic effects of the preparation, with antispasmodics - the effect of antispasmodics is enhanced.

Simultaneous use with methyldopa leads to a significant decrease in blood pressure, with probenecid - a decrease in the effect of probenecid.

It is possible to enhance the photosensitizing effect of other preparations that exhibit a photosensitizing effect (for example, sulfonamides, antibiotics of the tetracycline group and fluoroquinolones).

Overdose

Symptoms: an increase in the severity of side effects. later, these symptoms may be accompanied by a feeling of numbness, joint pain and a feeling of heaviness in the stomach. symptoms of nicotinamide overdose may also appear: dizziness, convulsions, tremors, sweating, cough, skin rash, arterial hypotension. symptoms characteristic of peripheral neuropathy.

Treatment: preparation withdrawal, symptomatic therapy prescribed by a doctor.

Storage conditions

In original packaging at a temperature not exceeding 25 ° С