Sinegra 100mg 4 tablets — Made in Turkey — Free Delivery

Compound

Contraindications

• hypersensitivity to the active substance or any of the excipients of the preparation;
• simultaneous use with nitric oxide donors (such as amyl nitrite) or nitrates in any form, since sildenafil is known to affect the metabolism of nitric oxide / cyclic guanosine monophosphate (cGMP) and potentiate the hypotensive effect of nitrates;
• the simultaneous use of PDE-5 inhibitors (including sildenafil) with guanylate cyclase stimulants, such as riociguat, is contraindicated, as it can lead to symptomatic hypotension;
• conditions in which sexual activity is not recommended (for example, severe cardiovascular disorders such as unstable angina or severe heart failure);
• loss of vision in one eye due to non-arterial anterior ischemic optic neuropathy, regardless of whether this pathology is associated with previous use of PDE-5 inhibitors or not;
• the presence of diseases such as severe liver dysfunction, arterial hypotension (blood pressure below 90/50 mm Hg), recent stroke or myocardial infarction, and known hereditary degenerative diseases of the retina, such as retinitis pigmentosa (a small number of these patients have genetic disorders retinal PDE), since the safety of sildenafil has not been studied in these patient subgroups.

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