Sumamed, powder for oral suspension 100mg/5 ml, 20 ml bottle (400 mg) 1 piece — Made in Croatia — Free Delivery
(Sumamed powder)
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Description Sumamed, powder for oral suspension 100mg/5 ml, 20 ml bottle (400 mg) 1 piece — Made in Croatia — Free Delivery
Indications for use
Upper and lower respiratory tract infections (streptococcal pharyngitis and tonsillitis, bacterial exacerbation of chronic obstructive pneumonia, interstitial and alveolar pneumonia, bacterial bronchitis), ENT organs (otitis media, laryngitis and sinusitis), genitourinary system (urethritis and cervicitis), skin tissues (erysipelas, impetigo, secondary infected dermatoses), chronic stage of erythema migrans (Lyme disease).
Method of administration and dosage
Inside, 1 hour before meals or 2 hours after meals, 1 time per day.
Contraindications
Hypersensitivity to macrolides, severe liver dysfunction, pregnancy, lactation.
pharmachologic effect
Pharmacological action - antibacterial. Suppresses protein biosynthesis, slowing down the growth and reproduction of bacteria; at high concentrations, a bactericidal effect is possible. Stable in an acidic environment, lipophilic, rapidly absorbed from the gastrointestinal tract. The maximum concentration is created in 2-3 hours, the half-life is 68 hours. A stable plasma level is achieved after 5-7 days. Easily passes histohematogenous barriers and enters the tissues. Concentrations in tissues and cells are 10-50 times higher than in plasma, and in the focus of infection - 24-34% higher than in healthy tissues. The high level (antibacterial) remains in the tissues for 5-7 days after the last injection. It is excreted in the bile (50%) unchanged and in the urine (6%). The spectrum of action is wide and includes gram-positive (Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus agalactiae, Streptococcus pneumoniae, Streptococcus pyogenes, streptococci, groups C, Fptococci) ), except for those resistant to erythromycin, and gram-negative (Haemophilus influenzae, Moraxella catarrhalis, Bordetella pertussis, Bordetella parapertussis, Campylobacter jejuni, Legionella pneumophila, Neisseria gonorrhoeae, Pardnerella, vaginalus spp.) microorganisms (Pardnerella, vaginalcus spp.) microorganisms (Pseudomonas spp. , chlamydia (Chlamydia trachomatis, Chlamydia pneumoniae), mycobacteria (Mycobacteria avium complex), mycoplasma (Mycoplasma pneumoniae), ureoplasma (Ureaplasma urealyticum), spirochetes (Treponema pallidum, Borrelia) burgdorferi.
Side effect
Nausea, vomiting, abdominal pain, constipation, flatulence, diarrhea, melena, cholestatic jaundice, chest pain, palpitations, weakness, drowsiness, headache, dizziness, nephritis, vaginitis, candidiasis, neutropenia or neutrophilia, pseudomembranous colitis, photosensitivity, rash , angioedema, eosinophilia; in children, in addition, hyperkinesia, agitation, nervousness, insomnia, conjunctivitis.
Interaction
Antacids containing aluminum or magnesium hydroxide reduce absorption and maximum concentration.
special instructions
Use with caution in case of severe violations of the liver, kidneys, cardiac arrhythmias. After discontinuation of treatment, hypersensitivity reactions in some patients may persist, which requires specific therapy under the supervision of a physician.
Storage conditions
List B. Store in a dry, dark place, at room temperature, out of the reach of children.
Tags: Sumamed
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