Supervit 30 chewable tablets — Made in Ukraine — Free Delivery

Pharmacological properties

Pharmacodynamics. A combined preparation that contains vitamins, macro- and microelements that regulate metabolic processes. the pharmacological action of the preparation is due to its constituent components.

Vitamin A (retinol acetate) ensures proper growth and normal condition of bones and epithelial tissues, vision and the immune system.

Vitamin D (cholecalciferol) regulates the metabolism of calcium and phosphorus.

Vitamin E (α-tocopherol acetate) prevents the oxidation of polyunsaturated fatty acids in membranes.

Vitamin B1 (thiamine hydrochloride) is an essential coenzyme in the metabolism of carbohydrates and the transmission of nerve impulses.

Vitamin B2 (riboflavin) is part of FMN and FAD (flavin mononucleotide and flavin adenine dinucleotide), which are predominantly necessary for metabolism.

Vitamin B6 (pyridoxine hydrochloride) is required for enzymes that take part in metabolism, as well as for the synthesis of neurotransmitters and hemoglobin.

Vitamin B12 (cyanocobalamin) functions as a coenzyme in the synthesis of nucleic acids and, together with folic acid, is involved in metabolic processes.

Nicotinamide (vitamin PP) is part of the cofactors NAD (H) and NADP (H) and part of the glucose tolerance factor.

Pantothenic acid (vitamin B5) functions primarily as part of coenzyme A and is involved in the production of hormones and antibodies.

Folic acid is necessary for cell division and metabolic processes together with vitamin B12.

Vitamin C (ascorbic acid) is essential for the growth and maintenance of bones, skin, teeth, capillary endothelium and the immune system.

Iron is essential for hemoglobin to function and as part of the oxygen reservoir in muscles.

Zinc is part of various enzymes, for example, for the synthesis and metabolism of fats and proteins.

Copper is used in metabolic reactions and in protein synthesis.

Manganese is an activator and provides various enzymatic reactions in the body.

Chromium is part of the glucose tolerance factor and is essential for normal metabolism.

Selenium works together with vitamin E to protect against oxidation and as a constituent of enzymes.

Iodine is an essential component of thyroid hormones.

Pharmacokinetics. Has not been investigated.

Indications

Prevention of vitamin and mineral deficiency in adults and treatment of children over the age of 4 years with insufficient intake of vitamins and minerals associated with improper diet and conditions that are accompanied by an increased need for vitamins and minerals (growth period, illness, recovery period) or in case of malabsorption (gastrointestinal diseases, diarrhea).

Application

Applied in adults and children aged 4 years and older, 1 tablet per day. apply orally with or immediately after meals. the tablets should be chewed.

The duration of the course of treatment is determined individually, depending on the patient's condition.

Contraindications

Hypersensitivity to preparation components, hypercalcemia, hypercalciuria, renal failure, nephrolithiasis, nephritis, nephrosis, nephrosonephritis, pulmonary tuberculosis (active form), fructose intolerance, glucose-galactose malabsorption syndrome, chronic glomerulonephritis, sarcoidosis, hypervitaminosis , thrombophlebitis, severe renal dysfunction, gout, hyperuricemia, phenylketonuria, erythremia, erythrocytosis, thromboembolism, thyrotoxicosis, chronic heart failure, active gastric ulcer and duodenal ulcer (due to possible increased acidity of gastric retinoids), metabolic disorders of iron or copper.

Side effects

When used in recommended doses, the preparation is usually well tolerated, however, adverse reactions may occur in persons with hypersensitivity.

From the immune system: allergic reactions, including anaphylactic shock, angioedema, hyperthermia;

on the part of the skin and subcutaneous tissue: skin rashes, urticaria, itching, skin redness, bronchospasm;

from the digestive tract: dyspeptic symptoms, nausea, vomiting, stomach pain, belching, constipation, diarrhea, increased secretion of gastric juice, heartburn;

from the nervous system: headache, dizziness, increased excitability, drowsiness;

others: visual impairment, increased sweating, possibly yellow urine.

With prolonged use of the preparation in high doses, irritation of the mucous membrane of the digestive tract, arrhythmia, paresthesia, hyperuricemia, decreased glucose tolerance, hyperglycemia, a transient increase in the activity of AST, LDH, ALP, impaired renal function, dryness and cracks in the palms and feet, prolapse hair, seborrheic rashes, changes in urine indicators, an increase in calcium in the blood and urine, calcification of soft tissues, kidneys, lungs, blood vessels, decreased blood clotting.

Special instructions

Prescribe with caution for liver lesions, peptic ulcers of the stomach and duodenum in history, cholelithiasis, chronic pancreatitis, patients with neoplasms, with a history of kidney disease, a tendency to thrombosis and bleeding (hemophilia, thrombocytopenia, thrombocytopathy).

The preparation can be used in the usual dose by patients with diabetes mellitus, as well as patients with gluten and milk intolerance.

The color of urine in yellow is possible, which is a completely harmless factor and is explained by the presence of riboflavin in the preparation.

Supervit is not recommended to be used together with other multivitamins and preparations containing trace elements, since an overdose is possible.

The preparation  contains lactose, so it should not be used in patients with rare hereditary forms of galactose intolerance, lactase deficiency or glucose-galactose malabsorption syndrome.

The medicinal product contains iodine, therefore, persons with thyroid disease should consult a doctor regarding the appropriateness of using the preparation.

Do not exceed the recommended dose.

Use during pregnancy and lactation. Since studies of the safety of the preparation during pregnancy and lactation have not been carried out, it should not be used in this category of patients.

Children. The preparation is used in children aged 4 years and older.

The ability to influence the reaction rate when driving or working with other mechanisms. Studies of the effect of the preparation  on the ability to drive a car or other (potentially dangerous) mechanisms have not been carried out. However, one should take into account the possibility of developing adverse reactions from the nervous system when using the preparation (drowsiness, dizziness).

Interactions

Vitamins a and e enhance each other's action and are synergistic. retinol reduces the anti-inflammatory effect of glucocorticoids. cannot be taken simultaneously with nitrites and cholestyramine, since they interfere with the absorption of retinol. vitamin a should not be taken at the same time as retinoids, as their combination is toxic.

Preparations containing iron inhibit the effect of vitamin E. Vitamin E should not be used together with preparations of iron, silver, agents with an alkaline medium (sodium bicarbonate, trisamine), indirect anticoagulants (dicumarin, neodikumarin). Alpha-tocopherol acetate enhances the action of steroid anti-inflammatory preparations and NSAIDs (sodium diclofenac, ibuprofen, prednisolone).

Vitamin C enhances the effect of sulfonamides (risk of crystalluria), penicillin, increases iron absorption, reduces the effectiveness of heparin and indirect anticoagulants. The absorption of vitamin C is reduced with simultaneous use with oral contraceptives.

Vitamin B1, influencing the polarization processes in the area of ​​neuromuscular synapses, can weaken the curariform effect. PASK, cimetidine, potassium preparations, alcohol reduce the absorption of vitamin B12.

Vitamin B6 weakens the effect of levodopa, prevents or reduces toxic manifestations that occur when using isoniazid and other anti-tuberculosis preparations.

Folic acid reduces plasma concentrations of phenytoin; with other antiepileptic preparations, a mutual decrease in clinical efficacy is possible.

Riboflavin is incompatible with streptomycin and reduces the effectiveness of antibacterial preparations (oxytetracycline, doxycycline, erythromycin, tetracycline and lincomycin).

The tricyclic antidepressants, imipramine and amitriptyline, inhibit the metabolism of riboflavin, especially in the tissues of the heart.

With simultaneous use with quinine, hemorrhages may increase. The activity of vitamin D3 may be reduced when used concomitantly with phenytoin or barbiturates. The preparation slows down the absorption of β-adrenergic receptor blockers and indirect anticoagulants.

In this regard, the preparation is recommended to be taken before or 2 hours after taking other preparations. To prevent a decrease in the absorption of thiophosphates or sodium fluoride, it is recommended to take the preparation no earlier than 1 hour after taking them.

With the simultaneous use of diuretics of the thiazide group, the risk of hypercalcemia increases. Cholestyramine, laxatives (paraffin oil) reduce the absorption of vitamin D3.

With the simultaneous use of antacid preparations containing aluminum, calcium, magnesium, there is a decrease in the absorption of iron, which is part of the preparation.

Overdose

Symptoms in case of an overdose of a preparation, an increase in the manifestations of adverse reactions, bloating is possible. in case of iron overdose, nausea, vomiting, diarrhea, abdominal pain, hematemesis, rectal bleeding, lethargy, acute vascular insufficiency are possible. hyperglycemia and acidosis may also occur.

An overdose of vitamin D3 leads to impairment of the cardiovascular system and kidneys.

Treatment. If signs of overdose appear, the use of tablets should be discontinued. Induce vomiting, introduce plenty of fluids, and follow a vitamin D3-limited diet. Further treatment is symptomatic.

Storage conditions

In its original packaging at a temperature not exceeding 25 ° C.