Antral 0.2g, 2p x 30 tablets — Made in Ukraine — Free Delivery

Product description

Antral belongs to the group of hepatoprotective preparations. It is effective in the treatment of acute and chronic hepatitis of various origins, liver cirrhosis, helps to reduce asthenovegetative disorders, improves appetite, sleep, and dyspeptic symptoms. With a course application, the preparation normalizes the content of bilirubin, γ-globulins, cholesterol in the blood, the prothrombin index, the activity of transaminases (ALT and ASAT) and alkaline phosphatase. Antral is characterized by prolonged anti-inflammatory, analgesic effects. According to the results of preclinical studies, it was found that Antral in conditions of acute, subacute and chronic liver damage by various xenobiotics and their combinations helps to weaken the effects of exposure to hepatotoxins, activate reparative processes in hepatocytes and practically normalize the parameters of the structural and functional state of the liver. The preparation inhibits the processes of lipid peroxidation in the blood and tissues, maintains the activity of the body's antioxidant systems, and stabilizes the structure of the liver and hepatocyte membranes. Being a relatively harmless pharmacological agent, Antral does not violate the functions of organs and body systems, it lacks cumulative properties, immunotoxic, local irritating, allergenic, ulcerogenic, embryotoxic, teratogenic effects.

The maximum accumulation of the preparation in the blood is observed after 3-4 hours, the half-life is 4-5 hours. The preparation is excreted in urine and feces.

Structure

active substance: 1 tablet contains antral in terms of dry matter 200 mg (0.2 g);

excipients: heavy magnesium carbonate, potato starch, crospovidone, microcrystalline cellulose, povidone, polysorbate, colloidal anhydrous silicon dioxide, calcium stearate, Opadry II 85 G18490 white, Opadry II 85 G25557 red.

Indications for use

Antral is indicated for adults and children for the treatment of: acute and chronic hepatitis of various origins (viral, alcoholic, medicinal, toxic); fatty degeneration and cirrhosis of the liver; inflammatory diseases of the gallbladder, spleen, pancreas; postcholecystectomy syndrome (after removal of the gallbladder). For the prevention of liver diseases due to the negative effects of toxins of various etiologies: alimentary toxins, preparations, chemotherapy, radiation therapy.

Contraindications

Individual hypersensitivity to preparation components.

Violation of renal excretory function.

Method of administration and dosage

Antral should be administered orally after meals 3 times a day:

adults and children from 10 years old - 200 mg per dose; with cirrhosis of the liver: in the first week of treatment - 400 mg per dose, then within 2-3 weeks - 200 mg per dose;

children 4-10 years old (including with cirrhosis of the liver) - 100 mg per dose.

The duration of treatment depends on the nature and severity of the disease. The average course of treatment is 3-4 weeks. The course of treatment should be repeated after 3-4 weeks.

Overdose.

In case of an overdose, the occurrence and intensification of adverse reactions is possible.

In case of accidental use of large doses of the preparation, you should rinse the stomach and (if necessary) carry out symptomatic treatment.

Adverse Reactions

The preparation is generally well tolerated by patients. In isolated cases, when using Antral, weakness, dizziness, dyspeptic symptoms, nausea, abdominal pain, diarrhea are possible, which disappear after the preparation is discontinued.

Allergic reactions, including skin rashes, urticaria, angioedema, redness and itching of the skin.

Application features

It is recommended to take Antral 20-30 minutes after a meal, with a sufficient amount of water or milk.

Use during pregnancy or lactation

Due to limited experience of use, the preparation is not recommended to be prescribed during pregnancy or lactation.

Children

The preparation should not be used in children under 4 years of age.

The ability to influence the reaction rate when driving or driving other mechanisms

No data is available on the impact, however, drivers and operators of complex machinery should be aware of the likelihood of developing dizziness.

Interaction with other medicinal products and other types of interactions

Antral is compatible with antibacterial, detoxifying, choleretic, vitamin preparations, which makes it possible to include it in complexes of therapeutic therapy. With simultaneous use in patients with liver cirrhosis, Antral does not affect the activity of steroid and cytostatic preparations; a decrease (up to 50-70%) of the previously used dose of steroids is allowed without further reducing the effectiveness of treatment.

Storage conditions

Store in its original packaging at a temperature not exceeding 25 ° C.

Keep out of the reach of children.

Shelf life is 3 years.

Do not use the preparation after the expiry date indicated on the package.