Neuroses accompanied by increased excitability, insomnia, hysteria; as part of the complex treatment of mild attacks of angina pectoris, angina pectoris of the initial stage, tachycardia of functional genesis, with spasms of the stomach and intestines, flatulence.

Barboval should be taken internally with a small amount of liquid or on a piece of sugar under the tongue.

Doses and duration of treatment are set by the doctor individually. Adults usually take 10-15 drops 2-3 times a day for 10-15 days.

It is better to take the preparation 20-30 minutes before meals.

After a break of 10-15 days, the course of treatment can be repeated.

Hypersensitivity to any components of the preparation, liver and kidney failure, hepatic porphyria, severe heart failure, severe arterial hypotension, acute myocardial infarction, diabetes, depression, myasthenia gravis, alcoholism, preparation and medication addiction, respiratory diseases with shortness of breath, obstructive syndrome .

Usually the preparation is well tolerated. the development of the following adverse reactions is possible:

Long-term use of bromine-containing preparations can lead to bromine poisoning, which is characterized by the following symptoms: CNS depression, depressed mood, confusion, ataxia, apathy, conjunctivitis, rhinitis, lacrimation, acne or purpura.

The presence of phenobarbital in the medicinal product can lead to the risk of developing Stevens-Johnson and Lyell syndrome, which is most likely in the first weeks of treatment. long-term use is not recommended due to the risk of preparation addiction, possible accumulation of bromine in the body and the development of bromine poisoning. in cases where the pain in the heart area does not go away after taking the preparation, it is necessary to consult a doctor to rule out acute coronary syndrome. the preparation should be prescribed with caution in arterial hypotension, hyperkinesis, hyperthyroidism, hypofunction of the adrenal glands, acute and constant pain, acute preparation intoxication.

Use during pregnancy or breastfeeding. The preparation should not be used by women during pregnancy or breastfeeding.

The ability to influence the speed of reaction when driving a motor vehicle or working with other mechanisms. The preparation can cause drowsiness and dizziness, therefore, during treatment, patients are not recommended to work with dangerous mechanisms and drive vehicles.

Children. There is no experience of using the preparation to treat children, so they are used in pediatric practice.

Simultaneous use with neuroleptics and tranquilizers potentiates, and with stimulants of the central nervous system - weakens the effect of each component of the preparation. barboval, containing derivatives of barbituric acid, enhances the effect of local anesthetics, analgesics and hypnotics. alcohol enhances the effects of the preparation and can increase its toxicity. the effect of the preparation increases against the background of the use of valproic acid preparations. the presence of phenobarbital in the composition of Barboval can induce liver enzymes, and this makes its simultaneous use with preparations that are metabolized in the liver (with coumarin derivatives, griseofulvin, glucocorticoids, oral contraceptives, cardiac glycosides, antimicrobial, antiviral, antifungal, antiepileptic, anticonvulsant , psychotropic, oral hypoglycemic, hormonal, immunosuppressive, cytostatic, antiarrhythmic, antihypertensive preparations, etc.), as their effectiveness will decrease as a result of a higher level of metabolism. MAO inhibitors prolong the effect of phenobarbital. rifampicin can reduce the effect of phenobarbital.

With the simultaneous use of phenobarbital with gold preparations, the risk of kidney damage increases.

With long-term use of phenobarbital with NSAIDs, there is a risk of stomach ulcers and bleeding.

Simultaneous use of phenobarbital with zidovudine increases the toxicity of both preparations