Corvalol 2p x 30 tablets — Made in Ukraine — Free Delivery
(Corvalol)
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Description Corvalol 2p x 30 tablets — Made in Ukraine — Free Delivery
Indication
Neurosis with increased irritability; insomnia; in complex therapy for hypertension and vegetative-vascular dystonia; sharply pronounced spasms of coronary vessels, tachycardia; intestinal spasms associated with neurovegetative disorders (as an antispasmodic preparation).
Application
Corvalol is prescribed sublingually (under the tongue) or inside for adults, 1 tablet 2-3 times a day.
If necessary (pronounced tachycardia and spasm of coronary vessels), a single dose can be increased to 3 tablets.
The duration of use of the preparation is determined by the doctor depending on the clinical effect and tolerability of the preparation.
Children. There is no experience of use for the treatment of children.
Contraindication
Increased sensitivity to the components of the preparation, bromine; pronounced liver and / or kidney function disorders; hepatic porphyria; severe heart failure; pronounced arterial hypotension; acute myocardial infarction; diabetes; depression; myasthenia; alcoholism; preparation and medicinal addiction; respiratory diseases with shortness of breath, obstructive syndrome.
Side effects
Corvalol is generally well tolerated. in some cases, the following side effects are possible:
- from the side of the digestive tract: constipation, a feeling of heaviness in the epigastric region, with long-term use - impaired liver function, nausea, discomfort in the stomach and intestines;
- from the nervous system: weakness, ataxia, impaired coordination of movements, nystagmus, hallucinations, paradoxical excitement, decreased concentration of attention, fatigue, slowing of reactions, headache, cognitive impairment, confusion, drowsiness, light dizziness;
- from the hematopoietic organs: anemia, thrombocytopenia, agranulocytosis;
- from the immune system: hypersensitivity reactions, including angioedema;
- from the side of the cardiovascular system: arterial hypotension, bradycardia, slowing of the heart rate;
- from the skin and mucous membrane: allergic reactions, including skin rashes, itching, urticaria, Stevens-Johnson syndrome, toxic epidermal necrolysis;
- other: difficulty breathing.
Long-term use of bromine-containing preparations can lead to bromine poisoning, characterized by the following symptoms: CNS depression, depressed mood, depression, confusion, ataxia, apathy, conjunctivitis, rhinitis, lacrimation, acne, or purpura.
Special instructions
The risk of developing Stevens-Johnson and Lyell syndrome is greatest in the first weeks of treatment. long-term use is not recommended due to the risk of preparation addiction, possible accumulation of bromine in the body and the development of bromine poisoning. in cases where the pain in the heart area does not go away after taking the preparation, it is necessary to consult a doctor to rule out acute coronary syndrome. cautiously prescribed for hyperkinesis, hyperthyroidism, hypofunction of the adrenal glands, decompensated heart failure, acute and constant pain, acute preparation intoxication.
Simultaneous consumption of alcoholic beverages should be avoided.
It is necessary to carefully prescribe the preparation in case of arterial hypotension.
The preparation contains lactose monohydrate, therefore, in case of intolerance to some sugars, a doctor's consultation is required before using this preparation.
Application during pregnancy and lactation. Do not use during pregnancy and breastfeeding.
The ability to influence the speed of reaction when driving a motor vehicle or working with other mechanisms. The preparation should not be taken by persons who work with mechanisms, drivers of motor vehicles, etc
Interactions
Preparations of the central depressant type of action enhance the effect of corvalol.
The presence of phenobarbital in the composition of the preparation can induce liver enzymes and, accordingly, can accelerate the metabolism of some preparations that are metabolized by these enzymes (including indirect anticoagulants, cardiac glycosides, antimicrobial, antiviral, antifungal, antiepileptic, anticonvulsant, psychotropic, oral hypoglycemic, hormonal, immunosuppressive , cytostatic, antiarrhythmic, antihypertensive preparations, griseofulvin, glucocorticoids, contraceptives), since their effectiveness will decrease as a result of a higher level of metabolism.
Corvalol enhances the effect of analgesics, local anesthetics and preparations that depress the central nervous system.
MAO inhibitors prolong the effect of phenobarbital. Rifampicin may reduce the effects of phenobarbital.
With the simultaneous use of phenobarbital with gold preparations, the risk of kidney damage increases.
With long-term simultaneous use of phenobarbital with NSAIDs, there is a risk of gastric ulcer formation and a risk of bleeding.
Simultaneous use of phenobarbital with zidovudine increases the toxicity of both preparations.
When used simultaneously with valproic acid, its effect increases.
With simultaneous use with methotrexate, the toxicity of the latter increases.
Alcohol enhances the effect of the preparation, and also increases its toxicity. Alcohol should be avoided while taking the preparation.
Overdose
Possible with frequent or long-term use of the preparation, which is associated with the accumulation of its components. long-term and constant use can cause addiction, withdrawal syndrome, psychomotor excitement. abrupt discontinuation of the preparation may cause a withdrawal syndrome.
Symptoms of overdose: suppression of breathing, until it stops; depression of the central nervous system, confusion, dizziness, ataxia, drowsiness, up to coma; suppression of cardiovascular activity, including rhythm disturbances, tachycardia, lowering of blood pressure, up to a collaptoid state; nausea, weakness, decrease in body temperature, decrease in diuresis.
Treatment: symptomatic.
Storage conditions
In a place protected from light at a temperature not higher than 25 °C. keep out of the reach of children.
Tags: Corvalol
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