Crestor 40mg 28 tablets — Made in Great Britain — Free Delivery

Product description

Crestor tablets are used for the following indications:

• treatment of hypercholesterolemia:
• adults, adolescents and children over 10 years of age with primary hypercholesterolemia (type IIa, including heterozygous familial hypercholesterolemia) or mixed dyslipidemia (type IIb) as an adjunct to diet, when dietary weight loss) is insufficient;
• with homozygous familial hypercholesterolemia as an adjunct to diet and other lipid-lowering treatments (eg LDL apheresis) or in cases where such treatment is inappropriate;
• prevention of cardiovascular disorders: prevention of significant cardiovascular disorders in patients who are estimated to be at high risk of a first case of cardiovascular disorder, in addition to correcting other risk factors.

Compound

Active substance: rosuvastatin;

1 coated tablet, 5 mg, 10 mg, 20 mg or 40 mg rosuvastatin as 5.20 mg, 10.40 mg, 20.80 mg 41.60 mg rosuvastatin calcium;

Excipients: lactose monohydrate, microcrystalline cellulose, calcium phosphate, crospovidone, magnesium stearate film shell: lactose monohydrate, hypromellose, glycerin triacetate, titanium dioxide (E 171), for tablets of 5 mg - iron oxide yellow (E172) for tablets of 10 mg, 20 mg, 40 mg - iron oxide red (E 172).

Contraindications

• patients with hypersensitivity to rosuvastatin or any of the excipients of the preparation;
• patients with active liver disease, including persistent elevations in serum transaminases of unknown etiology and any elevations in serum transaminases, which are three times higher than the upper limit of normal (UHN);
• patients with severe renal impairment (creatinine clearance <30 ml / minute);
• patients with myopathy;
• patients who are simultaneously receiving cyclosporine;
• during pregnancy and lactation, as well as women of reproductive age who do not use proper contraception.

Mode of application

Before starting treatment, the patient should be prescribed a standard cholesterol-lowering diet, which he should adhere to during treatment. The dose should be selected individually, depending on the goal of therapy and the patient's response to treatment, guided by the recommendations of the current generally accepted guidelines.

The preparation Crestor can be taken at any time of the day, regardless of the meal.

Application features

Pregnant

Contraindicated.

Children

The use of the preparation for children should be carried out only by a specialist.

Drivers

Carefully.

Overdose

There is no specific treatment for overdose. In case of an overdose, the patient should be treated symptomatically and, if necessary, supportive measures should be taken. It is necessary to monitor liver function and CK levels. Hemodialysis is unlikely to be effective.

Side effects

Adverse events that are noted with the use of the preparation Crestor are usually mild and temporary. In controlled clinical trials, less than 4% of patients receiving Crestor withdrew from the study due to adverse reactions.

Below are the most common adverse reactions to rosuvastatin according to clinical studies and extensive experience with post-registration use.

Endocrine disorders: frequent (from ≥ 1/100 to <1/10) - diabetes mellitus.

From the nervous system: frequent (from ≥ 1/100 to <1/10) - headache, dizziness.

From the gastrointestinal tract: frequent (from ≥ 1/100 to <1/10) - constipation, nausea, abdominal pain.

On the part of skeletal muscles and connective tissue: frequent (from ≥ 1/100 to <1/10) - myalgia.

Interaction

During the period of combined use of the preparation Crestor and cyclosporin, the AUC value of rosuvastatin was, on average, about 7 times higher than those observed in healthy volunteers. Crestor is contraindicated in patients receiving cyclosporine at the same time.

Storage conditions

Store at a temperature not exceeding 30 ° C, out of the reach of children.

Shelf life is 3 years.