Eroton 50mg 1 tablet — Made in Ukraine — Free Delivery

(Eroton 50mg)
Eroton 50mg 1 tablet — Made in Ukraine — Free Delivery
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Fitofarm Brand: Fitofarm
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Description Eroton 50mg 1 tablet — Made in Ukraine — Free Delivery

Product description

Sildenafil is an oral preparation used to treat erectile dysfunction in men. With sexual arousal, the preparation restores reduced erectile function by increasing blood flow to the penis.

The physiological mechanism that leads to an erection, including the release of nitric oxide (NO) in the corpora cavernosa during sexual arousal. The released nitric oxide activates the enzyme guanylate cyclase, which stimulates an increase in the level of cyclic guanosine monophosphate (cGMP), which, in turn, causes relaxation of the smooth muscles of the corpora cavernosa, promoting blood flow.

Sildenafil is a potent and selective inhibitor of cGMP-specific phosphodiesterase 5 (PDE-5) in the corpora cavernosa, where PDE-5 is responsible for the breakdown of cGMP. The effects of sildenafil on erection are peripheral. Sildenafil does not have a direct relaxing effect on isolated human cavernous bodies, but powerfully enhances the relaxing effect of NO on this tissue. When the metabolic pathway NO / cGMP is activated, which occurs during sexual stimulation, inhibition of PDE5 by sildenafil leads to an increase in the level of cGMP in the corpora cavernosa. Thus, in order for sildenafil to cause a pharmacological effect, sexual arousal is necessary.

Indications

The preparation is recommended for men with erectile dysfunction, which is defined as the inability to achieve or maintain an erection of the penis necessary for successful intercourse.

For the effective action of the preparation, sexual arousal is necessary.

Contraindications

Hypersensitivity to sildenafil or any of the excipients of the preparation, simultaneous use with nitric oxide donors (such as amyl nitrite) or nitrates in any form is contraindicated, since it is known that sildenafil affects the pathways of nitric oxide / cyclic guanosine monophosphate (cGMP) metabolism and potentiates the hypotensive effect of nitrates ; conditions in which sexual activity is undesirable (severe cardiovascular disorders such as unstable angina pectoris or severe heart failure).

Taking the preparation is contraindicated in patients who have lost vision in one eye due to non-arterial anterior ischemic neuropathy of the optic nerve, regardless of whether this pathology is associated with previous use of PDE-5 inhibitors or not.

The presence of such diseases as severe liver dysfunction, arterial hypotension (blood pressure below 90/50 mm Hg. Art.), Recent stroke or myocardial infarction and known hereditary degenerative diseases of the retina, such as retinitis pigmentosa (a small number of such patients have genetic retinal PDE disorders), since the safety of sildenafil has not been investigated in such patient subgroups.

Method of administration and dosage

The preparation is administered orally.

Adults. The recommended dose is 50 mg, applied if necessary, approximately 1:00 before sexual activity. Depending on the effectiveness and tolerability of the preparation , the dose can be increased to 100 mg or reduced to 25 mg. The maximum recommended dose is 100 mg. The frequency of application of the maximum recommended dose of the preparation is 1 time per day. When using the preparation during a meal, the effect of the preparation may occur later than when it is used on an empty stomach.

Children. The preparation is indicated for use by persons under 18 years of age.

Overdose

When using a single dose of sildenafil up to 800 mg, adverse reactions were similar to those observed with sildenafil at lower doses, but were more frequent and more severe. The use of sildenafil at a dose of 200 mg did not lead to an increase in efficacy, but caused an increase in the number of cases of adverse reactions (headache, hot flashes, dizziness, dyspepsia, nasal congestion, visual disturbances).

In case of overdose, if necessary, you should resort to the usual supportive measures. An acceleration of the clearance of sildenafil during hemodialysis is unlikely due to the high degree of binding of the preparation to blood plasma proteins and the lack of elimination of sildenafil in the urine.

Structure

active substance: sildenafil;

1 tablet contains sildenafil citrate in doses equivalent to 50 mg or 100 mg of sildenafil;

Excipients: calcium hydrogen phosphate dihydrate, microcrystalline cellulose, copolyvidone, colloidal silicon dioxide, talc, magnesium stearate, croscarmellose sodium, potato starch.

Storage conditions

Store in its original packaging at a temperature not exceeding 25 ° C.

Keep out of the reach of children.

The shelf life is 5 years.

Tags: Eroton

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