Locoid cream 1mg/g 30g — Made in Italy — Free Delivery
(Locoid )
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Description Locoid cream 1mg/g 30g — Made in Italy — Free Delivery
Product description
Locoid cream is used in conditions when there is a response to treatment with corticosteroids (eczema, dermatitis, psoriasis). Topical corticosteroids are generally not indicated for the treatment of psoriasis, but may be acceptable, with the exception of common plaque psoriasis, provided precautions are taken.
Compound
The active ingredient is hydrocortisone 17-butyrate (1 g of cream contains 1 mg of hydrocortisone 17-butyrate).
Excipients: cetostearyl alcohol, macrogol cetostearyl ether, mineral light oil, white soft paraffin, propyl parahydroxybenzoate (E 216), butyl parahydroxybenzoate, anhydrous citric acid, sodium citrate, purified water.
Contraindications
Except in cases of treatment in combination with appropriate chemotherapeutic agents:
- skin lesions (wounds) caused by bacterial infections (eg pyoderma, syphilitic or tuberculous lesions), viral infections (eg chickenpox, herpes simplex, herpes zoster, common wart, flat wart, genital warts, molluscum contagiosum); infections caused by fungi and yeast; parasitic infections (eg scabies);
- ulcerative skin lesions;
- adverse reactions caused by corticosteroids (eg, perioral dermatitis, striae);
- ichthyosis, juvenile plantar dermatosis, acne vulgaris, rosacea, fragility of skin vessels, skin atrophy;
- allergic reactions of hypersensitivity to the components of the preparation or corticosteroids (the latter are rare);
- skin neoplasms.
Mode of application
For cutaneous use.
Apply the preparation in a small amount with a thin even layer to the affected areas no more than 2 times a day.
May be applied under an occlusive dressing for more persistent lesions such as thickened psoriatic plaques on the elbows and knees (excluding oozing lesions).
The total course dose should not exceed 30-60 g of cream per week.
The same doses are used in adults and elderly patients, since there is no clinical evidence indicating that elderly patients need a special dosing regimen.
Application features
Pregnant
Data on the use of hydrocortisone butyrate in pregnant women are lacking or limited. The results of studies on laboratory animals indicate the reproductive toxicity of the preparation. Corticosteroids cross the placenta. With the systemic use of large doses of corticosteroids, the effect on the fetus or newborn child (fetal growth retardation, adrenocortical suppression) has been reported. Despite the small amount of information on the use of corticosteroids on the skin of pregnant women, given the limited systemic absorption of preparations in this group, it is possible to use corticosteroids of weak and moderate action (class 1 and class 2), such as hydrocortisone, for short periods of time and on limited skin areas ... The aforementioned effects cannot be ruled out with prolonged use or when applied to large areas of the skin. This can only be done with special indications.
Hydrocortisone butyrate / metabolites pass into breast milk, however, when using the preparation in therapeutic doses, exposure to newborns / breastfed infants is not expected. The preparation can be used by women during lactation only under conditions of short-term treatment and application to small areas of the skin. With long-term treatment or application to large areas of affected skin, breastfeeding should be discontinued.
Children
Long-term treatment should be avoided if possible. From 6 months to one year of age - if possible, the treatment period should last a maximum of 7 days.
Drivers
There is no data on the effect of the preparation on the ability to drive vehicles or other mechanisms, the occurrence of the effect is not expected.
Overdose
With excessive use under an occlusive dressing, suppression of the adrenal glands may occur. There is no specific treatment or antidote. If any side effects occur, treatment should be discontinued and symptomatic treatment should be carried out.
Side effects
Skin and subcutaneous tissue disorders: rarely (> 1/10000, <1/1000) - dermatitis, eczema, striae, contact dermatitis; contact allergy, pustular acne; skin atrophy, often irreversible, accompanied by thinning of the epidermis, telangiectasias, purple and stretch marks; depigmentation, hypertrichosis; rosacea-like and perioral dermatitis, with or without skin atrophy; "Rebound effect", which can lead to steroid dependence; delayed wound healing; skin infection, redness, irritation, burning, rash, itching, dry skin, folliculitis, prickly heat, acne, maceration.
Endocrine disorders: rarely (> 1/10000, <1/1000) - adrenocortical suppression, Cushing's syndrome, hyperglycemia, glucosuria, growth retardation and intracranial hypertension.
From the side of the organs of vision: very rarely (<1/10000, including individual messages) - increased intraocular pressure and the risk of cataracts (with systematic ingestion of the preparation on the conjunctiva).
From the immune system: very rarely (<1/10000, including individual messages) - hypersensitivity reactions.
Storage conditions
Store in its original packaging at a temperature not exceeding 25 ° C, out of the reach of children. Do not refrigerate.
Shelf life is 3 years.
Tags: Locoid
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