Olfen transdermal patch, for external use 140mg / 12hours, 2pcs — Made in Germany by Teva — Free Delivery
(Olfen)
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Description Olfen transdermal patch, for external use 140mg / 12hours, 2pcs — Made in Germany by Teva — Free Delivery
Pharmacological properties
Olfen transdermal patch - NSAID with analgesic properties, is intended for topical use. the therapeutic effect is due to the inhibitory effect of sodium diclofenac on the synthesis of prostaglandins.
With local use of the preparation Olfen transdermal patch, the active substance penetrates through the skin, reaching the subcutaneous tissues, and has an analgesic, anti-inflammatory effect, reduces tissue edema. When the Olfen transdermal patch was used in patients with significant sports injuries, the preparation showed an effective analgesic effect compared to placebo.
The concentration of diclofenac in tissues is maintained by constant penetration from the patch and does not depend on the time of day. The average concentration of the substance in the blood plasma is ≈3 ng / ml.
The mechanism of metabolism and excretion of diclofenac after topical application corresponds to that for oral administration of diclofenac sodium preparations. T½ is 1–2 hours.
Indications
Local short-term treatment:
inflammation of tendons, ligaments, muscles and joints of traumatic etiology, for example, with sprains of ligaments and tendons, dislocations, bruises;
localized forms of rheumatism of soft tissues and joints.
Application
The patch is applied to the affected area of the body. apply 1 patch 2 times a day, morning and evening. before use, remove the transparent film that protects the surface of the patch. one transdermal patch is designed for continuous use for 12 hours.
The maximum daily dose is 2 patches, even if, if necessary, apply the patch on more than one area. Can only be used in one area at a time.
The patch should be applied for as short a period as possible.
The duration of treatment should not exceed 7 days.
Contraindications
Hypersensitivity to diclofenac, acetylsalicylic acid, other NSAIDs, analgesics or to any component of the preparation. a history of BA attacks, urticaria, or acute rhinitis due to the use of acetylsalicylic acid or other NSAIDs. exacerbation of stomach and duodenal ulcers, open skin lesions, burns, skin infections, or eczema.
Side effects
On the part of the skin and subcutaneous fat: often - redness, itching, burning and rash on the skin, sometimes with pustules or blisters; infrequently - hypersensitivity reactions, local allergic reactions, including contact dermatitis; the frequency is unknown - in patients who used NSAIDs for the cutaneous, generalized skin rash, hypersensitivity reactions, including angioedema, anaphylactic reactions, photosensitivity reactions were noted.
When using the preparation on large areas for a long period, the appearance of systemic side effects (such as kidney or gastrointestinal tract disease, bronchospasm) is possible, but the risk of their occurrence is very low compared to oral administration of preparations with diclofenac sodium.
special instructions
Olfen transdermal patch should not be applied to open wounds (eg, scratches, cuts) or to eczematous skin areas. avoid contact with eyes and mucous membranes.
If after 3 days of treatment the patient's condition has not improved or worsened, you should consult a doctor.
To reduce the risk of side effects, it is necessary to use the minimum effective dose of diclofenac sodium for treatment for as short a period as possible.
Patients with allergies or asthma with a history of NSAID use may develop bronchospasm.
If any skin rash appears after using the preparation, treatment should be discontinued.
Avoid direct sunlight or solarium radiation at the site of application for about 1 day to reduce the risk of photosensitization.
Despite the fact that the risk of systemic side effects is minimal, the preparation Olfen transdermal patch should be used with caution in patients with impaired renal, heart or liver function, with a history of stomach and duodenal ulcers, intestinal phlegmon or hemorrhagic diathesis.
Elderly patients should use NSAIDs with caution because of the greater predisposition to side effects.
Olfen transdermal patch contains propylene glycol and dibutylhydroxytoluene. Propylene glycol can irritate the skin. Dibutylhydroxytoluene may cause local skin reactions (eg contact dermatitis) or irritation of the eyes and mucous membranes.
It is not recommended to use any other NSAIDs or medicines containing diclofenac while using the Olfen transdermal patch.
Use during pregnancy or lactation
I and II trimester. There is no sufficient clinical data regarding the cutaneous use of diclofenac during pregnancy. In animal studies, reproductive toxicity was revealed after systemic use of the preparation.
Suppression of prostaglandin synthesis can adversely affect pregnancy and / or embryo fetal development. Data from epidemiological studies indicate an increased risk of miscarriage, heart defects and gastroschisis after the use of prostaglandin synthesis inhibitors in early pregnancy. It is believed that this risk increases with the dose of preparations and the duration of therapy.
In the first and second trimester of pregnancy, the dose should be minimal, and the duration of treatment should be as short as possible.
III trimester. Diclofenac sodium is contraindicated in the third trimester of pregnancy due to the fact that all inhibitors of prostaglandin synthesis can:
cause in the fetus:
- cardiopulmonary toxicity (with premature closure of the ductus arteriosus and the development of pulmonary hypertension);
- impaired renal function, progressing to renal failure with oligohydramnios;
cause in mother and child:
- prolonged bleeding - an effect associated with inhibition of platelet aggregation, which can manifest itself even with the use of the preparation in very low doses;
- inhibition of contractions of the muscles of the uterus, which leads to a delay or prolongation of labor.
Lactation. A small amount of diclofenac and its metabolites pass into breast milk. The decision on the use of the preparation during lactation is made by the doctor if there are substantial grounds for its use, when the expected benefit from treatment outweighs the potential risk. Olfen transdermal patch should not be applied to the breasts or large areas of the skin and should not be applied for a long time.
The ability to influence the reaction rate when driving or operating other mechanisms. It is unlikely to have a negative effect.
Children. The efficacy and safety of the preparation Olfen transdermal patch for children under the age of 18 have not been studied.
Interactions
Systemic absorption of diclofenac with the correct use of the preparation olfen transdermal patch is very low compared to oral administration, therefore, interaction with other preparations is unlikely.
Overdose
Overdose cases were not observed.
If, with incorrect use or accidental overdose of the Olfen transdermal patch, systemic side effects occur, appropriate measures should be taken, as in the case of intoxication with oral NSAIDs.
Storage conditions
At a temperature not exceeding 25 ° c. Shelf life after the first opening of the package is 4 months if stored at a temperature not exceeding 25 ° C and 6 months - if stored at a temperature of 2-8 ° C (in a refrigerator).
Tags: Olfen
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