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  • Pectolvan Stop syrup 25 ml — Made in Ukraine — Free Delivery

Pectolvan Stop syrup 25 ml — Made in Ukraine — Free Delivery

(Pectolvan Stop)
Pectolvan Stop syrup 25 ml — Made in Ukraine — Free Delivery
Pectolvan Stop syrup 25 ml — Made in Ukraine — Free Delivery
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Farmak Brand: Farmak
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Description Pectolvan Stop syrup 25 ml — Made in Ukraine — Free Delivery

Pharmacological properties

Pharmacodynamics. A combined preparation that has an antitussive, mucolytic and expectorant effect. citrate, which is part of the butamirate preparation, belongs to antitussive substances of peripheral action, does not cause dependence, does not depress the respiratory center.
The antitussive effect of citrate butamirate is complemented by the expectorant effect of guaifenesin, which enhances the secretion of the bronchial glands, reduces the viscosity of sputum and thereby improves its discharge.
Pharmacokinetics. Butamirate citrate after oral administration is rapidly and completely absorbed, 98% binds to blood plasma proteins. It is metabolized to form two metabolites that have an antitussive effect, more than 90% of which are excreted in the urine; only a small amount is excreted in the feces. Biological T½ is about 6 hours.
Guaifenesin after oral administration is rapidly absorbed in the gastrointestinal tract. A small part of it binds to blood plasma proteins. Excreted in the urine, mainly in the form of metabolites, a small amount - unchanged. Biological T½ is 1 hour.

Indications

Dry, irritating, paroxysmal cough of various origins. the preparation can be used to eliminate cough in the pre- and postoperative period.

Application

Used internally. take preferably after meals. Dissolve the appropriate number of drops in 100 ml of liquid (water, tea, fruit juice). the interval between doses should be 4-6 hours.
Dosing should be adhered to depending on the patient's body weight:
up to 7 kg - 8 drops 3-4 times a day;
7-12 kg - 9 drops 3-4 times a day;
12-20 kg - 14 drops 3-4 times a day;
20-30 kg - 14 drops 3-4 times a day;
30-40 kg - 16 drops 3-4 times a day;
40-50 kg - 25 drops 3 times a day;
50–70 kg - 30 drops 3 times a day;
70–90 kg - 40 drops 3 times a day.
The maximum daily dose of guaifenesin for children aged 6 months to 2 years is 300 mg / day (3 ml of the preparation, or 99 drops), for children aged 2-6 years - 600 mg / day (6 ml of the preparation, or 198 drops ), 6-12 years - 1200 mg / day (12 ml of the preparation), for adults and children over the age of 12 years - 2400 mg / day (24 ml of the preparation).
Drinking more fluids increases the effectiveness of the treatment. If Pectolvan Stop is prescribed for very young children (weighing 7 kg), then the dose can be reduced. Even if the child does not drink all 100 ml of the liquid with the preparation dissolved in it, the number of drops of the preparation (total concentration) in the liquid must not be increased.
Do not use the preparation for more than 7 days without consulting a doctor.

Contraindications

Hypersensitivity to the components of the preparation, myasthenia gravis.

Side effects

If the recommended dosage is adhered to, the preparation is usually well tolerated. side effects usually disappear after lowering the dose of the preparation.
From the side of metabolism: lack of appetite;
from the nervous system: headache, drowsiness;
on the part of the organ of hearing and balance: dizziness;
from the respiratory system: shortness of breath;
from the digestive tract: a feeling of discomfort in the digestive tract, nausea, stomach pain, vomiting, diarrhea;
from the urinary system: urolithiasis;
from the immune system: allergic reactions, including anaphylactic shock, angioedema, skin rashes, itching, urticaria.

Special instructions

The preparation should not be used in patients with BA, chronic bronchitis or emphysema, productive cough and / or persistent or chronic cough associated with smoking.
Use the preparation with caution in tuberculosis, pneumoconiosis.
If the cough persists or gets worse, treatment should be reviewed.
Pectolvan Stop contains 34.3 vol.% Ethanol (alcohol), that is, up to 350 mg when taking the maximum single dose (40 drops), which is equivalent to approximately 8 ml of beer or 3 ml of wine when taking the maximum single dose. This can have undesirable consequences for alcoholics. The presence of ethanol should be considered when treating women who are pregnant or breastfeeding, as well as children and people in high-risk groups such as patients with liver disease or epilepsy.
If an intolerance to some sugars has been established, you should consult your doctor before taking this medicine.
Use during pregnancy and lactation. There have been no controlled studies in pregnant women or in animals. An increase in the number of cases of inguinal hernia in newborns was reported with the use of guaifenesin in the first trimester of pregnancy. Therefore, the preparation is contraindicated in the first trimester of pregnancy.
The use of the preparation in the II and III trimester of pregnancy or during lactation is possible only in cases where, in the opinion of the doctor, the expected therapeutic effect for the mother outweighs the potential risk for the fetus / child.
It is not known whether butamirate citrate or guaifenesin passes into breast milk. For safety reasons, it is necessary to carefully weigh the benefits and risks of using the preparation during breastfeeding.
Children. The preparation can be used in children from 6 months of age according to indications.
The ability to influence the reaction rate when driving or working with other mechanisms. Rarely, the preparation can cause drowsiness, which may to some extent affect the ability to drive vehicles or operate other mechanisms. Therefore, be careful when driving or performing other work requiring care (such as driving mechanical means).

Interactions

Since butamirate inhibits the cough reflex, concomitant use of expectorants should be avoided, as this can lead to stagnation of mucus in the airways, which increases the risk of bronchospasm and respiratory tract infection.
Lithium and magnesium enhance the effect of guaifenesin.
Guaifenesin enhances the analgesic effect of paracetamol and acetylsalicylic acid, enhances the effect of alcohol and other substances that depress the central nervous system.
Muscle relaxants with a central mechanism of action can increase the unwanted effects of guaifenesin, especially muscle weakness.
Guaifenesin can cause false positive results in diagnostic tests for 5-hydroxyindoleacetic acid (photometric method using nitrosonaphthol as a reagent) and vanilyl mandelic acid in urine. It is necessary to stop treatment with Pectolvan Stop 48 hours before urine collection for this analysis.

Overdose

In case of an overdose, signs of the toxic effect of guaifenesin predominate - drowsiness, nausea, vomiting, muscle weakness.
There may also be such signs of an overdose as diarrhea, dizziness, arterial hypotension. X-ray negative urolithiasis is possible.
There is no specific antidote.
Treatment. Gastric lavage, intake of activated charcoal. Symptomatic therapy is aimed at maintaining the functions of the cardiovascular and respiratory systems, kidney function and electrolyte balance.

Storage conditions

In original packaging at a temperature not exceeding 25 ° c. do not freeze.

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