Posterisan Forte 25g Ointment | Relief & Buy Online

Posterisan Forte is a high-potency proctological preparation designed to provide rapid relief during acute flare-ups of hemorrhoidal disease and severe inflammatory conditions of the perianal area. Unlike the standard version, the Forte formulation combines the immunomodulatory benefits of bacterial lysates with the powerful anti-inflammatory properties of hydrocortisone. This dual-action approach is specifically engineered to target intense itching, significant swelling, and acute pain that often accompany advanced hemorrhoids or severe anal eczema. By simultaneously suppressing excessive inflammation and stimulating local tissue immunity, Posterisan Forte helps stabilize the affected area, allowing for a faster transition to the healing phase while providing immediate symptomatic comfort.

Composition and Active Substance

Each 1 gram of Posterisan Forte ointment contains:

• Active Substances: 166.7 mg of a standardized suspension of bacterial culture (CSBC), containing at least 500 million inactivated Escherichia coli bacteria (including cell wall components and metabolic products) and 2.5 mg of Hydrocortisone.

• Preservative: 3.3 mg of Liquefied Phenol.

• Excipients: Lanolin (wool fat), white soft paraffin (petrolatum), and antioxidants.

Pharmacological Action

The efficacy of Posterisan Forte lies in its synergistic dual mechanism:

1. Anti-Inflammatory & Antipruritic: Hydrocortisone, a low-potency corticosteroid, works rapidly to reduce capillary permeability, stabilize lysosomal membranes, and suppress the release of inflammatory mediators. This leads to a significant reduction in redness, swelling, and the burning sensation.

2. Immunomodulatory Effect: The bacterial lysates (E. coli) act as a local vaccine, stimulating macrophages and T-lymphocytes within the anal mucosa. This increases the production of Secretory Immunoglobulin A (sIgA) and enhances the resistance of the tissue to secondary infections.

3. Regenerative Support: By balancing the immune response, the ointment promotes the restoration of the mucosal barrier and the healing of anal fissures.

Indications for Use

• Acute Hemorrhoids: Specifically for episodes characterized by significant inflammation and pain.

• Severe Anal Pruritus: Relief of intense, non-responsive itching in the perianal region.

• Anal Fissures: Treatment of painful tears with associated inflammatory swelling.

• Perianal Eczema: Management of allergic or irritant-driven skin inflammation surrounding the anus.

• Proctitis: Inflammation of the rectal lining in its acute phase.

Contraindications

• Infections: Primary viral (e.g., herpes, varicella), fungal (candidiasis), or specific bacterial (tuberculosis, syphilis) infections in the application area.

• Hypersensitivity: Known allergy to hydrocortisone, phenol, lanolin, or bacterial lysates.

• Vaccination Reactions: Should not be used in the anal area if a post-vaccination reaction is present nearby.

• Pregnancy: Strictly contraindicated in the first trimester.

Dosage and Administration

Posterisan Forte is intended for local application in the anal and rectal area.

• Standard Regimen: Apply a thin layer of ointment 2 to 3 times daily (morning, evening, and potentially after each bowel movement).

• External Use: Rub gently into the affected skin areas.

• Internal Use: For internal symptoms, use the provided applicator. Screw the applicator onto the tube, insert it into the rectum, and squeeze gently to dispense the medication.

Special Administration Tips

Because this product contains a corticosteroid, it is designed for short-term use. Treatment should generally not exceed 10 days. Once the acute symptoms have subsided, it is often recommended to switch to the regular (non-steroid) Posterisan ointment to maintain local immunity and complete the healing process.

Side Effects and Adverse Reactions

When used according to instructions, side effects are rare, but may include:

• Local Reactions: Mild burning, stinging, or allergic contact dermatitis (often due to lanolin or phenol).

• Steroid-Related: If used for more than 2-3 weeks, there is a risk of skin atrophy (thinning of the skin), telangiectasia (visible small blood vessels), or secondary infections.

• Systemic Effects: Minimal absorption occurs, but very long-term use over large areas could theoretically lead to systemic corticosteroid effects.

Special Precautions & Warnings

• Pregnancy and Lactation: Use during the second and third trimesters only if prescribed by a doctor. Avoid long-term use during breastfeeding.

• Latex Caution: The fats in the ointment can weaken latex condoms, increasing the risk of breakage.

• Hygiene: Always clean the applicator with warm water and soap after every internal use to prevent contamination.

• Diagnosis: If symptoms do not improve within 5-7 days, consult a proctologist to ensure no underlying malignancy or infection is present.

Storage Conditions and Shelf Life

• Store at room temperature, not exceeding 25°C.

• Do not freeze, as this can break the emulsion of the ointment.

• Shelf Life: 3 years. After opening, ensure the cap is tightly closed to prevent the ointment from drying out.

• Keep out of reach of children.