Bacterial lysates, or immunization vaccines for children
- 01 December 2020 10:13:46
- Views: 1158
Bacterial
lysates are immunizing vaccines that can protect the body against recurrent
respiratory diseases. They are administered orally, in the form of tablets,
granules, capsules, or aerosols. They are available only by prescription and
can usually be used by children over 3 years of age.
Why do we get sick?
Respiratory tract infections are the most common cause of
medical appointments, especially in children. An infection is considered to be
recurrent in children aged 2 to 4 years when it occurs 6 to 8 times a year.
Most children go through 20-30 infections in the first 4 years of life.
However, this is not a cause for concern and does not constitute grounds for
suspecting an immune disorder. Infections are a necessary part of the immune
system's development. Through contact with antigens, the body learns to fight
this type of threat. Childhood infections are extremely common due to the number
of microorganisms and ongoing contact with peers in nurseries, kindergartens,
and schools. In older children, infections are considered to be recurrent when
they take place 6 or more times within a single year.
There are a number of factors that may contribute to the
frequent occurrence of infections. These include:
environmental
factors (exposure to pollution)
allergies,
in some
cases, serious immunity disorders, which parents are so often unnecessarily
worried about,
insufficient
physical activity,
poor sleep
hygiene,
stress,
bad eating
habits.
Recurrent
infections can also be caused by excessive and unjustified use of antibiotics.
One often-overlooked factor is the exposure to tobacco smoke breathed by the
child's parents or guardians, which has a very large impact on the infections'
frequency.
How does vaccine immunization work?
Vaccines are biological preparations administered to develop
resistance to certain pathogenic microorganisms. The antigens contained in
vaccines, when introduced into the body are supposed to simulate a natural
infection and push the body to develop immunity similar to that which it would
produce through a real infection. This allows for the production of antibodies
and the creation of an immune memory, which translates into much better
response to the disease upon repeated infection.
Since
humanity is currently facing an impending antibiotics crisis, new methods of
fighting infections are constantly being sought. One of the devised solutions
is the administration of oral, non-specific vaccines called bacterial lysates.
Bacterial lysates are dead, chemically or enzymatically lysed bacterial cells
or fragments thereof. Unlike most classic, specific vaccines, they are
introduced into the body orally. They contain many different types of bacteria,
especially those responsible for respiratory tract infections, including:
Streptococcus
pneumoniae,
Streptococcus
pyogenes,
Staphylococcus
aureus,
Moraxella
catarrhalis,
Neisseria
cararrhalis,
Klebsiella
pneumoniae,
Haemophilus
influenzae.
Vaccines
work on immunity by stimulating the body's natural defenses. As a result of
contact with the antigen, the level of natural immunoglobulins, mainly IgA,
increases, which protect the mucous membranes such as those found in the
respiratory system. The fight against bacterial antigens contained in the
lysate serves as a training battle for the specific immune system.
Research
has shown that lysates exhibit the ability to reduce infections caused by both
bacteria and viruses other than those that were used to manufacture the
preparation.
The mere
presence of various antigens stimulates the mechanisms of non-specific
immunity, which is what gives lysates their ability to potentially help fight
off viruses. Therefore, lysates stimulate both the specific (mainly through
granulocytes, mast cells, and NK cells) and the nonspecific immune system
(through T and B lymphocytes). This stimulation causes intensive
synthesis of immunoglobulins: IgA, IgE, IgG, IgM, and cytokines. Due to their
non-specific function, lysates can provide a better immune response to various
pathogens, including those with which the body faces for the first time. This
makes for more effective protection in the event of various types of
infections.
Immunization vaccines – who are they for?
Numerous
scientific studies have proven that lysates help reduce the frequency of
seasonal infections of the respiratory system, which in turn decreases the need
for the consumption of antibiotics.
Clinical
studies have shown that bacterial lysates can reduce the incidence of
infections in children and adults by up to 30-40%.
For
children, orally administered immunization vaccines can play a significant part
in the prevention of frequently recurring respiratory diseases, such as
pharyngitis, laryngitis, tonsillitis, or angina, as well as bronchitis,
sinusitis, and inner ear inflammation. Some oral vaccines have shown
effectiveness both in prophylaxis and in therapy.
Non-specific
vaccines come in the form of tablets, capsules, granules, and aerosols. Some of
them can be given to children from the age of 2, but most of them only from the
age of 3. Immunization vaccines are products that should not be used without
medical supervision and are therefore only available by prescription. They
should only be taken after excluding any abnormalities in the structure and
functioning of the respiratory system.
In summary,
stimulating the body's immune system with bacterial lysates is a very effective
method of preventing both bacterial and viral respiratory infections. The
safety of their use has been confirmed by numerous scientific studies. Acquiring
immunity as a result of oral vaccination is a long-term process, sometimes
taking several months, as the body's immune mechanisms are gradually
stimulated. It is worth considering beginning the therapy in the summer to
prepare the child's immune system for the challenges waiting for it during the
fall and winter.
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